ATP2B4: Difference between revisions

Jump to navigation Jump to search
m (Bot: HTTP→HTTPS)
imported>Bibcode Bot
m (Adding 0 arxiv eprint(s), 1 bibcode(s) and 0 doi(s). Did it miss something? Report bugs, errors, and suggestions at User talk:Bibcode Bot)
 
Line 25: Line 25:
*{{cite journal | author=Strehler EE |title=Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane |journal=J. Biol. Chem. |volume=265 |issue= 5 |pages= 2835–42 |year= 1990 |pmid= 2137451 |doi= |name-list-format=vanc| author2=James P | author3=Fischer R | display-authors=3 | last4=Heim | first4=R | last5=Vorherr | first5=T | last6=Filoteo | first6=AG | last7=Penniston | first7=JT | last8=Carafoli | first8=E }}
*{{cite journal | author=Strehler EE |title=Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane |journal=J. Biol. Chem. |volume=265 |issue= 5 |pages= 2835–42 |year= 1990 |pmid= 2137451 |doi= |name-list-format=vanc| author2=James P | author3=Fischer R | display-authors=3 | last4=Heim | first4=R | last5=Vorherr | first5=T | last6=Filoteo | first6=AG | last7=Penniston | first7=JT | last8=Carafoli | first8=E }}
*{{cite journal | author=James P |title=Identification and primary structure of a calmodulin binding domain of the Ca<sup>2+</sup> pump of human erythrocytes |journal=J. Biol. Chem. |volume=263 |issue= 6 |pages= 2905–10 |year= 1988 |pmid= 2963820 |doi= |name-list-format=vanc| author2=Maeda M | author3=Fischer R | display-authors=3 | last4=Verma | first4=AK | last5=Krebs | first5=J | last6=Penniston | first6=JT | last7=Carafoli | first7=E }}
*{{cite journal | author=James P |title=Identification and primary structure of a calmodulin binding domain of the Ca<sup>2+</sup> pump of human erythrocytes |journal=J. Biol. Chem. |volume=263 |issue= 6 |pages= 2905–10 |year= 1988 |pmid= 2963820 |doi= |name-list-format=vanc| author2=Maeda M | author3=Fischer R | display-authors=3 | last4=Verma | first4=AK | last5=Krebs | first5=J | last6=Penniston | first6=JT | last7=Carafoli | first7=E }}
*{{cite journal | author=Brandt P |title=A C-terminal, calmodulin-like regulatory domain from the plasma membrane Ca<sup>2+</sup>-pumping ATPase |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 9 |pages= 2914–8 |year= 1988 |pmid= 2966397 |doi=10.1073/pnas.85.9.2914 | pmc=280113 |name-list-format=vanc| author2=Zurini M | author3=Neve RL | display-authors=3 | last4=Rhoads | first4=RE | last5=Vanaman | first5=TC }}
*{{cite journal | author=Brandt P |title=A C-terminal, calmodulin-like regulatory domain from the plasma membrane Ca<sup>2+</sup>-pumping ATPase |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 9 |pages= 2914–8 |year= 1988 |pmid= 2966397 |doi=10.1073/pnas.85.9.2914 | pmc=280113 |name-list-format=vanc| author2=Zurini M | author3=Neve RL | display-authors=3 | last4=Rhoads | first4=RE | last5=Vanaman | first5=TC |bibcode=1988PNAS...85.2914B }}
*{{cite journal | vauthors=Howard A, Barley NF, Legon S, Walters JR |title=Plasma-membrane calcium-pump isoforms in human and rat liver |journal=Biochem. J. |volume=303 |issue= Pt 1|pages= 275–9 |year= 1994 |pmid= 7945253 |doi= 10.1042/bj3030275| pmc=1137587 }}
*{{cite journal | vauthors=Howard A, Barley NF, Legon S, Walters JR |title=Plasma-membrane calcium-pump isoforms in human and rat liver |journal=Biochem. J. |volume=303 |issue= Pt 1|pages= 275–9 |year= 1994 |pmid= 7945253 |doi= 10.1042/bj3030275| pmc=1137587 }}
*{{cite journal | vauthors=Stauffer TP, Hilfiker H, Carafoli E, Strehler EE |title=Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes |journal=J. Biol. Chem. |volume=269 |issue= 50 |pages= 32022 |year= 1995 |pmid= 7989379 |doi= }}
*{{cite journal | vauthors=Stauffer TP, Hilfiker H, Carafoli E, Strehler EE |title=Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes |journal=J. Biol. Chem. |volume=269 |issue= 50 |pages= 32022 |year= 1995 |pmid= 7989379 |doi= }}

Latest revision as of 16:39, 22 June 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Plasma membrane calcium-transporting ATPase 4 is an enzyme that in humans is encoded by the ATP2B4 gene.[1][2]

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.[2]

Interactions

ATP2B4 has been shown to interact with CASK.[3]

References

  1. Olson S, Wang MG, Carafoli E, Strehler EE, McBride OW (Jul 1991). "Localization of two genes encoding plasma membrane Ca2(+)-transporting ATPases to human chromosomes 1q25-32 and 12q21-23". Genomics. 9 (4): 629–41. doi:10.1016/0888-7543(91)90356-J. PMID 1674727.
  2. 2.0 2.1 "Entrez Gene: ATP2B4 ATPase, Ca++ transporting, plasma membrane 4".
  3. Schuh, Kai; Uldrijan Stjepan; Gambaryan Stepan; Roethlein Nicola; Neyses Ludwig (Mar 2003). "Interaction of the plasma membrane Ca2+ pump 4b/CI with the Ca2+/calmodulin-dependent membrane-associated kinase CASK". J. Biol. Chem. United States. 278 (11): 9778–83. doi:10.1074/jbc.M212507200. ISSN 0021-9258. PMID 12511555.

Further reading

External links