Ventricular septal defect post-surgical prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]and Leida Perez, M.D.; Associate Editor-In-Chief: Keri Shafer, M.D. [2], Priyamvada Singh, MBBS

Post-operative Treatment

Post-operative course

  • The operative mortality for an elective repair is less than 2%.
  • It is increased by the presence of associated anomalies, multiple defects, or if there is severe pulmonary hypertension.
  • Late follow-up shows that their life expectancy is restored to that of age matched controls (except in those over the age of three with severe pulmonary hypertension).
  • There is a residual defect in 14% to 25% of patients which is hemodynamically insignificant
  • In patients over 3 at the time of the operation, there is often residual and progressive pulmonary hypertension and or residual ventricular dysfunction.
  • The risk of endocarditis following closure is similar to that in the general population. Because small defects are frequent, antibiotic prophylaxis is still recommended.

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