Tongue cancer other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2] Mohammed Abdelwahed M.D[3]

Overview

Other diagnostic studies for tongue cancer include tumor biopsy and panendoscopy. Tumor biopsy helps to evaluate viable tumor cells. The majority of biopsy findings reflect the presence of squamous cell carcinoma. Panendoscopy is highly accurate for evaluation of smaller or more superficial second primary mucosal lesions.

Other Diagnostic Studies

Tumor biopsy

  • A sample of the lesion may be obtained as a part of the endoscopic evaluation of the tumor or in the clinical setting.
  • Tumor biopsy helps to evaluate viable tumor cells. The majority of biopsy findings reflect the presence of squamous cell carcinoma.
  • However, in fewer instances, minor salivary gland malignancies and sarcomas are discovered.[1]

Panendoscopy

  • Panendoscopy allows for the complete evaluation of the upper aerodigestive tract and helps rule out the presence of a metachronous tumor.
  • With the help of panendoscopy, the mucous membranes of the upper aerodigestive tract are evaluated, and biopsy samples of any abnormal tissue areas are taken for assessment.
  • By performing tumor-specific endoscopy an intermediate view is obtained, whereby the anesthetized patient in a relaxed state can have the oral cavity examined with less difficulty. The tumor is staged after completing the evaluation.
  • Panendoscopy is highly accurate for evaluation of smaller or more superficial second primary mucosal lesions.[2]

References

  1. Liu J, Wang XL, Liu L, Xue LY, Liu K, Huang H; et al. (2013). "[Application value of sentinel node biopsy in early stage oral tongue cancer with clinically negative neck]". Zhonghua Zhong Liu Za Zhi. 35 (6): 459–62. PMID 24119908.
  2. Kim SY, Roh JL, Yeo NK, Kim JS, Lee JH, Choi SH; et al. (2007). "Combined 18F-fluorodeoxyglucose-positron emission tomography and computed tomography as a primary screening method for detecting second primary cancers and distant metastases in patients with head and neck cancer". Ann Oncol. 18 (10): 1698–703. doi:10.1093/annonc/mdm270. PMID 17716985.

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