Thrombotic thrombocytopenic purpura physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
The presence of fever, purpura, petechiae, paleness in physical examination is highly suggestive of TTP.
Physical Examination
Skin
- Bruising may be present even in mucous membrane called purpura
- Pinpoint dots on skin called petechiae
- Paleness
- Jaundice
Heart
- Dyspnea
- Arrhythmia
- Severe complications; sudden cardiac death, myocardial infarction, cardiogenic shock, heart failure
Neurologic
- No abnormalities
- Moderate signs [1]; speech changes, confusion
- Severe involvement: focal signs, seizure, stroke, coma
Renal
Other
Urine
- Dark urine
References
- ↑ Scully M, Yarranton H, Liesner R, Cavenagh J, Hunt B, Benjamin S; et al. (2008). "Regional UK TTP registry: correlation with laboratory ADAMTS 13 analysis and clinical features". Br J Haematol. 142 (5): 819–26. doi:10.1111/j.1365-2141.2008.07276.x. PMID 18637802.