Subependymal giant cell astrocytoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2], Sujit Routray, M.D. [3]

Overview

On head CT, some of the findings that are suggestive of subependymal giant cell astrocytoma include a heterogenous mass with uniform post contrast enhancement, enlargement of the ventricles, and iso- or slightly hypoattenuating to grey matter.

CT

Head CT scan may be helpful in the diagnosis of subependymal giant cell astrocytoma. Findings on CT scan suggestive of/diagnostic of subependymal giant cell astrocytoma include:[1][2][3][4]

Axial brain CT scan showing an intraventricular mass in the right foramen of Monro area, with cystic and solid components and small areas of calcification. There is a contrast enhancement of solid component. Also multiple calcified subependymal nodules are seen source:Case courtesy of Dr Ilkhom Nalibaev, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/48054">rID: 48054</a>


References

  1. Jung TY, Kim YH, Jung S, Baek HJ, Lee KH (2015). "The clinical characteristics of subependymal giant cell astrocytoma: five cases". Brain Tumor Res Treat. 3 (1): 44–7. doi:10.14791/btrt.2015.3.1.44. PMC 4426277. PMID 25977907.
  2. Stein JR, Reidman DA (2016). "Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis". Case Rep Radiol. 2016: 3750450. doi:10.1155/2016/3750450. PMC 4752974. PMID 26942030.
  3. Moran V, O'Keeffe F (1986). "Giant cell astrocytoma in tuberous sclerosis: computed tomographic findings". Clin Radiol. 37 (6): 543–5. doi:10.1016/s0009-9260(86)80009-5. PMID 3791849.
  4. Beaumont, Thomas L.; Godzik, Jakub; Dahiya, Sonika; Smyth, Matthew D. (2015). "Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report". Journal of Neurosurgery: Pediatrics. 16 (2): 134–137. doi:10.3171/2015.1.PEDS13146. ISSN 1933-0707.


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