Felty's syndrome

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

Felty's syndrome is a condition characterized by the triad of rheumatoid arthritis, splenomegaly and granulocytopenia.^[1]

Historical Perspective

It is named for A. R. Felty.^[2]^[3]

Classification

Pathophysiology

Causes

Differentiating Felty's Syndrome from Other Diseases

Epidemiology and Demographics

Age

Gender

Race

Risk Factors

Natural History, Complications and Prognosis

Recurrent Infection,
Hypersplenism → causing 2° anaemia ± thrombocytopenia
Lymphadenopathy
Skin hyperpigmentation & cutaneous ulceration

Diagnosis

Diagnostic Criteria

Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Treatment is similar to that of rheumatoid arthritis. Splenectomy may improve neutropenia in severe disease.

Surgery

Prevention

References

↑ Degowin, Elmer. Bedside Diagnositc Examiniation. MacMillan Publishing, New York. 1981. Page 894. ISBN 0023280301.
↑ Template:WhoNamedIt
↑ A. R. Felty. Chronic arthritis in the adult, associated with splenomegaly and leucopenia. A report of 5 cases of an unusual clinical syndrome. Bulletin of the Johns Hopkins Hospital, Baltimore, 1924, 35: 16.

Template:Diseases of the musculoskeletal system and connective tissue

Template:WikiDoc Sources

[deg-1] Degowin, Elmer. Bedside Diagnositc Examiniation. MacMillan Publishing, New York. 1981. Page 894. ISBN 0023280301.

[2] Template:WhoNamedIt

[3] A. R. Felty. Chronic arthritis in the adult, associated with splenomegaly and leucopenia. A report of 5 cases of an unusual clinical syndrome. Bulletin of the Johns Hopkins Hospital, Baltimore, 1924, 35: 16.

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