STAMBP

STAM binding protein
Identifiers
Symbols	STAMBP ; AMSH; MGC126516; MGC126518
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4719
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

STAM binding protein, also known as STAMBP, is a human gene.

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Further reading

• Andersson B, Wentland MA, Ricafrente JY; et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yu W, Andersson B, Worley KC; et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. PMID 9110174.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Asada H, Ishii N, Sasaki Y; et al. (1999). "Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT". J. Exp. Med. 189 (9): 1383–90. PMID 10224278.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tanaka N, Kaneko K, Asao H; et al. (1999). "Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines". J. Biol. Chem. 274 (27): 19129–35. PMID 10383417.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Endo K, Takeshita T, Kasai H; et al. (2000). "STAM2, a new member of the STAM family, binding to the Janus kinases". FEBS Lett. 477 (1–2): 55–61. PMID 10899310.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Itoh F, Asao H, Sugamura K; et al. (2001). "Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads". EMBO J. 20 (15): 4132–42. doi:10.1093/emboj/20.15.4132. PMID 11483516.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ishii N, Owada Y, Yamada M; et al. (2001). "Loss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice". Mol. Cell. Biol. 21 (24): 8626–37. doi:10.1128/MCB.21.24.8626-8637.2001. PMID 11713295.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maytal-Kivity V, Reis N, Hofmann K, Glickman MH (2006). "MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function". BMC Biochem. 3: 28. PMID 12370088.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ibarrola N, Kratchmarova I, Nakajima D; et al. (2004). "Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signaling". BMC Cell Biol. 5: 2. doi:10.1186/1471-2121-5-2. PMID 14728725.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ambroggio XI, Rees DC, Deshaies RJ (2006). "JAMM: a metalloprotease-like zinc site in the proteasome and signalosome". PLoS Biol. 2 (1): E2. doi:10.1371/journal.pbio.0020002. PMID 14737182.CS1 maint: Multiple names: authors list (link)
• Li H, Seth A (2004). "An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein". Oncogene. 23 (10): 1801–8. doi:10.1038/sj.onc.1207319. PMID 14755250.
• McCullough J, Clague MJ, Urbé S (2004). "AMSH is an endosome-associated ubiquitin isopeptidase". J. Cell Biol. 166 (4): 487–92. doi:10.1083/jcb.200401141. PMID 15314065.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hillier LW, Graves TA, Fulton RS; et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Row PE, Prior IA, McCullough J; et al. (2006). "The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation". J. Biol. Chem. 281 (18): 12618–24. doi:10.1074/jbc.M512615200. PMID 16520378.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nakamura M, Tanaka N, Kitamura N, Komada M (2006). "Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes". Genes Cells. 11 (6): 593–606. doi:10.1111/j.1365-2443.2006.00963.x. PMID 16716190.CS1 maint: Multiple names: authors list (link)
• Tsang HT, Connell JW, Brown SE; et al. (2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003. PMID 16730941.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)