SLC16A4

Solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
Identifiers
Symbols	SLC16A4 ; MCT5; MCT4
External IDs	Template:OMIM5 Template:MGI HomoloGene: 74529
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SLC16A4 205234 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Solute carrier family 16, member 4 (monocarboxylic acid transporter 5), also known as SLC16A4, is a human gene.

See also

• Solute carrier family

Further reading

• Halestrap AP, Price NT (1999). "The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation". Biochem. J. 343 Pt 2: 281–99. PMID 10510291.
• Halestrap AP, Meredith D (2004). "The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond". Pflugers Arch. 447 (5): 619–28. doi:10.1007/s00424-003-1067-2. PMID 12739169.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Price NT, Jackson VN, Halestrap AP (1998). "Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past". Biochem. J. 329 ( Pt 2): 321–8. PMID 9425115.CS1 maint: Multiple names: authors list (link)
• Pilegaard H, Terzis G, Halestrap A, Juel C (1999). "Distribution of the lactate/H+ transporter isoforms MCT1 and MCT4 in human skeletal muscle". Am. J. Physiol. 276 (5 Pt 1): E843–8. PMID 10329977.CS1 maint: Multiple names: authors list (link)
• Manning Fox JE, Meredith D, Halestrap AP (2001). "Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle". J. Physiol. (Lond.). 529 Pt 2: 285–93. PMID 11101640.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Philp NJ, Wang D, Yoon H, Hjelmeland LM (2003). "Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells". Invest. Ophthalmol. Vis. Sci. 44 (4): 1716–21. PMID 12657613.CS1 maint: Multiple names: authors list (link)
• Juel C, Holten MK, Dela F (2004). "Effects of strength training on muscle lactate release and MCT1 and MCT4 content in healthy and type 2 diabetic humans". J. Physiol. (Lond.). 556 (Pt 1): 297–304. doi:10.1113/jphysiol.2003.058222. PMID 14724187.CS1 maint: Multiple names: authors list (link)
• Settle P, Mynett K, Speake P; et al. (2004). "Polarized lactate transporter activity and expression in the syncytiotrophoblast of the term human placenta". Placenta. 25 (6): 496–504. doi:10.1016/j.placenta.2003.11.009. PMID 15135232.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wilson MC, Meredith D, Fox JE; et al. (2005). "Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)". J. Biol. Chem. 280 (29): 27213–21. doi:10.1074/jbc.M411950200. PMID 15917240.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Merezhinskaya N, Ogunwuyi SA, Fishbein WN (2006). "Expression of monocarboxylate transporter 4 in human platelets, leukocytes, and tissues assessed by antibodies raised against terminal versus pre-terminal peptides". Mol. Genet. Metab. 87 (2): 152–61. doi:10.1016/j.ymgme.2005.09.029. PMID 16403666.CS1 maint: Multiple names: authors list (link)
• Bickham DC, Bentley DJ, Le Rossignol PF, Cameron-Smith D (2006). "The effects of short-term sprint training on MCT expression in moderately endurance-trained runners". Eur. J. Appl. Physiol. 96 (6): 636–43. doi:10.1007/s00421-005-0100-x. PMID 16408234.CS1 maint: Multiple names: authors list (link)
• Ullah MS, Davies AJ, Halestrap AP (2006). "The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism". J. Biol. Chem. 281 (14): 9030–7. doi:10.1074/jbc.M511397200. PMID 16452478.CS1 maint: Multiple names: authors list (link)
• Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bishop D, Edge J, Thomas C, Mercier J (2007). "High-intensity exercise acutely decreases the membrane content of MCT1 and MCT4 and buffer capacity in human skeletal muscle". J. Appl. Physiol. 102 (2): 616–21. doi:10.1152/japplphysiol.00590.2006. PMID 17082373.CS1 maint: Multiple names: authors list (link)