Proerythroblast
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| Proerythroblast (Image courtesy of Melih Aktan M.D.) |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast.
Laboratory findings
In histology, it is very difficult to distinguish it from the other "blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast.) The cytoplasm is blue in an H&E stain, indicating that it is basophilic.
"Pronormoblast" vs. "proerythroblast"
Some sources consider the terms "pronormoblast" and "proerythroblast" to be synonyms.[1] However, other sources[2] consider "proerythroblast" to be a parent term, divided into the following two categories:
- "pronormoblast" - normal develoment
- "promegaloblast" - abnormal development
Additional images
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Blood cell lineage
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Proerythroblasts
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Proerythroblasts
References
External links
- Histology image: 01804loa – Histology Learning System at Boston University - "Bone Marrow and Hemopoiesis: bone marrow smear, erythroblast series with proerythroblast"
- Template:OklahomaHistology
- Histology at KUMC blood-blood04
- Image and description at purdue.edu
- Histology of "promegaloblast" at marist.edu (pernicious anemia)
- Interactive image at usuarios.lycos.es
- Overview at temple.edu
Template:Skin and subcutaneous tissue symptoms and signs Template:Nervous and musculoskeletal system symptoms and signs Template:Urinary system symptoms and signs Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:Speech and voice symptoms and signs Template:General symptoms and signs
Template:SIB cs:Proerytroblast id:Rubriblas sk:Proerytroblast