PNPLA2

Patatin-like phospholipase domain containing 2
Identifiers
Symbols	PNPLA2 ; 1110001C14Rik; ATGL; DKFZp667M109; FP17548; PEDF-R; TTS-2.2; TTS2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 10687
Gene ontology Biological process Template:GNF GO
RNA expression pattern
File:PBB GE PNPLA2 212705 x at tn.png
File:PBB GE PNPLA2 39854 r at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Patatin-like phospholipase domain containing 2, also known as PNPLA2, is a human gene.

Further reading

• Andersson B, Wentland MA, Ricafrente JY; et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yu W, Andersson B, Worley KC; et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. PMID 9110174.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Colland F, Jacq X, Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Villena JA, Roy S, Sarkadi-Nagy E; et al. (2004). "Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis". J. Biol. Chem. 279 (45): 47066–75. doi:10.1074/jbc.M403855200. PMID 15337759.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jenkins CM, Mancuso DJ, Yan W; et al. (2005). "Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities". J. Biol. Chem. 279 (47): 48968–75. doi:10.1074/jbc.M407841200. PMID 15364929.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zimmermann R, Strauss JG, Haemmerle G; et al. (2004). "Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase". Science. 306 (5700): 1383–6. doi:10.1126/science.1100747. PMID 15550674.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Smirnova E, Goldberg EB, Makarova KS; et al. (2006). "ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells". EMBO Rep. 7 (1): 106–13. doi:10.1038/sj.embor.7400559. PMID 16239926.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schoenborn V, Heid IM, Vollmert C; et al. (2006). "The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes". Diabetes. 55 (5): 1270–5. PMID 16644682.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lass A, Zimmermann R, Haemmerle G; et al. (2007). "Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome". Cell Metab. 3 (5): 309–19. doi:10.1016/j.cmet.2006.03.005. PMID 16679289.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mairal A, Langin D, Arner P, Hoffstedt J (2007). "Human adipose triglyceride lipase (PNPLA2) is not regulated by obesity and exhibits low in vitro triglyceride hydrolase activity". Diabetologia. 49 (7): 1629–36. doi:10.1007/s00125-006-0272-x. PMID 16752181.CS1 maint: Multiple names: authors list (link)
• Wilson PA, Gardner SD, Lambie NM; et al. (2006). "Characterization of the human patatin-like phospholipase family". J. Lipid Res. 47 (9): 1940–9. doi:10.1194/jlr.M600185-JLR200. PMID 16799181.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Notari L, Baladron V, Aroca-Aguilar JD; et al. (2007). "Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor". J. Biol. Chem. 281 (49): 38022–37. doi:10.1074/jbc.M600353200. PMID 17032652.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fischer J, Lefèvre C, Morava E; et al. (2007). "The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy". Nat. Genet. 39 (1): 28–30. doi:10.1038/ng1951. PMID 17187067.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rydén M, Jocken J, van Harmelen V; et al. (2007). "Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis". Am. J. Physiol. Endocrinol. Metab. 292 (6): E1847–55. doi:10.1152/ajpendo.00040.2007. PMID 17327373.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jocken JW, Langin D, Smit E; et al. (2007). "Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state". J. Clin. Endocrinol. Metab. 92 (6): 2292–9. doi:10.1210/jc.2006-1318. PMID 17356053.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Steinberg GR, Kemp BE, Watt MJ (2007). "Adipocyte triglyceride lipase expression in human obesity". Am. J. Physiol. Endocrinol. Metab. 293 (4): E958–64. doi:10.1152/ajpendo.00235.2007. PMID 17609260.CS1 maint: Multiple names: authors list (link)
• Fischer J, Negre-Salvayre A, Salvayre R (2007). "[Neutral lipid storage diseases and ATGL (adipose triglyceride lipase) and CGI-58/ABHD5 (alpha-beta hydrolase domain-containing 5) deficiency: myopathy, ichthyosis, but no obesity]". Med Sci (Paris). 23 (6–7): 575–8. PMID 17631826.CS1 maint: Multiple names: authors list (link)