OctreoScan

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

OctreoScan is a kit for the preparation of Indium In-111 pentetreotide, a diagnostic radiopharmaceutical.

Indications for OctreoScan imaging

• Tumor evaluation

• Pheochromocytoma
• Paraganglioma
• Islet cell tumor
• Carcinoid
• Medullary carcinoma of thyroid
• Small cell lung cancer
• Neuroblastoma
• Pituitary adenoma
• Lymphoma
• Breast cancer
• Astrocytoma
• Meningioma
• Thymoma

Patient preparation

• Bowel preparation with laxative and enema
• Discontinue octeotide therapy for 1 week prior the exam

Radiopharmaceutical

• In-111 OctreoScan

Dose and route of administration

• 6 mCi IV
  • 4 hours (abdomen, pelvis)
  • 24 hours (whole body)

Equipment

• Camera: Large field of view SPECT gamma camera
• Collimator: Medium-energy
• Window: 20% window around 173 and 245 KeV

Procedure

• 4 hours: Planar images of the abdomen and pelvis
• 24 hours: Planar images of the whole body. SPECT of regions of clinical concern.

Images

Images courtesy of RadsWiki

Normal OctreoScan

References

• Ziessman, Harvey A, O'Malley, Janis P, and Thrall, James M. Nuclear Medicine: The Requisites. 3rd ed. Philadelphia, Pennsylvania: Mosby, 2006. ISBN 0323029469

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