Norethandrolone

Norethandrolone

Gene therapy
Clinical data
Other names	(8R,9S,10R,13S,14S,17S)-17-Ethyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
AHFS/Drugs.com	International Drug Names
ATC code	A14AA09 (WHO)
Physiological data
Legal status
Pharmacokinetic data
Identifiers
IUPAC name (17β)-17-ethyl-17-hydroxyester-4-en-3-one
CAS Number	52-78-8
PubChem Template:Abbreviation	5858
ChemSpider	5649 Y
UNII	P7W01638W6
KEGG	D07127 Y
Chemical and physical data
Formula	C20H30O2
Molar mass	302.451 g/mol
3D model (JSmol)	Interactive image
SMILES O=C4\C=C3/[C@@H]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)CC)[C@@H]2CC3)C)CC4
InChI InChI=1S/C20H30O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h12,15-18,22H,3-11H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1 Y Key:ZDHCJEIGTNNEMY-XGXHKTLJSA-N Y
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sree Teja Yelamanchili, MBBS [2]

Overview

Norethandrolone is an anabolic steroid. This drug was approved for sale by the U.S. Food and Drug Administration (FDA) in 1965 under the trade name Nilevar and finds legitimate use as an androgen for cases of hormonal deficiency, treatment of patients with severe burns, after severe trauma and for certain forms of aplastic anemia. It is now only marketed in Australia, France and Switzerland, and as with all 17-alpha alkylated oral steroids, long-term use in high doses result in elevated liver enzymes and consequently cirrhosis.

References

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