Neuromyelitis optica spectrum disorder electrocardiogram
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Julinka Auta Fernandes
Overview
For neuromyelitis optica spectrum disorder (NMOSD), an electrocardiogram (ECG) is not included in the international consensus diagnostic criteria. Consequently, ECG alone cannot confirm or exclude NMOSD.[1][2]
Key ECG Findings in Neuromyelitis Optica Spectrum Disorder
Neuromyelitis optica spectrum disorder has no characteristic diagnostic ECG pattern specified in the cited diagnostic recommendations, including the 2026 consensus guidelines from the Middle East and North Africa Committee for Treatment and Research in Multiple Sclerosis (MENACTRIMS).[2][3]
Indications for Electrocardiography
In neuromyelitis optica spectrum disorder accompanied by syncope, the following indications for ECG testing come from the general European Society of Cardiology (ESC) syncope guideline:
- Initial ECG: An ECG forms part of the initial evaluation of syncope.[4]
- Rhythm monitoring: Immediate ECG monitoring is indicated when arrhythmic syncope is suspected. In-hospital monitoring, including telemetry, is warranted when high-risk clinical features suggest arrhythmic syncope.[4]
References
- ↑ Wingerchuk DM, Banwell B, Bennett JL, et al. (2015). "International consensus diagnostic criteria for neuromyelitis optica spectrum disorders". Neurology. 85 (2): 177–189. doi:10.1212/WNL.0000000000001729. PMC 4515040. PMID 26092914.
- ↑ 2.0 2.1 Jarius S, Aktas O, Ayzenberg I, et al. (2023). "Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis". Journal of Neurology. 270 (7): 3341–3368. doi:10.1007/s00415-023-11634-0. PMC 10267280 Check
|pmc=value (help). PMID 37022481 Check|pmid=value (help). - ↑ Yamout B, Gouider R, Al-Roughani R, et al. (2026). "Consensus Recommendations for the Diagnosis and Treatment of Neuromyelitis Optica Spectrum Disorders (NMOSD): The MENACTRIMS Guidelines". CNS Drugs. 40 (3): 283–303. doi:10.1007/s40263-025-01260-x. PMID 41591715 Check
|pmid=value (help). - ↑ 4.0 4.1 Brignole M, Moya A, de Lange FJ, et al. (2018). "2018 ESC Guidelines for the diagnosis and management of syncope". European Heart Journal. 39 (21): 1883–1948. doi:10.1093/eurheartj/ehy037. PMID 29562304.