Mediastinitis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]
Overview
If left untreated, fibrosing mediastinitis may progress to sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.[2] Common complications of mediastinitis include sepsis and pneumonia.
Natural History
If left untreated, fibrosing mediastinitis may progress to sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, with some estimates predicting rates greater than 60%.[2]
Complications
Common complications of mediastinitis include the following:[1][3]
Prognosis
Generally, patients with mediastinitis have a poor prognosis with a mortality rate near 40%.[4] Mediastinitis among post-sternotomy patients has a particularly poor prognosis with an elevated risk of mortality near 60%.[2] Prognosis improves with antimicrobial therapy.[1]
References
- ↑ 1.0 1.1 1.2 1.3 Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.
- ↑ 2.0 2.1 2.2 Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A (2011). "[Mediastinitis]". Arch Bronconeumol. 47 Suppl 8: 32–6. doi:10.1016/S0300-2896(11)70065-5. PMID 23351519.
- ↑ Fibrosing Mediastinitis. National Organization for Rare Disorders (2015). https://rarediseases.org/rare-diseases/fibrosing-mediastinitis/ Accessed on September 25, 2015
- ↑ Macrí P, Jiménez MF, Novoa N, Varela G (2003). "[A descriptive analysis of a series of patients diagnosed with acute mediastinitis]". Arch. Bronconeumol. (in Spanish; Castilian). 39 (9): 428–30. PMID 12975075.