Lupus nephritis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]
Overview
The incidence of lupus nephritis is 34 to 51 percent in Blacks, 31 to 43 percent in Hispanics, 33 to 55 percent in Asians, and 14 to 23 percent in Whites. In 2005, Incidence was fiund to be 5.1 (Overall), 1.9 (Adult men), 8.2 (Adult women).The incidence of Lupus nephritis increases with age upto 50 years; the median age at diagnosis is 25 years.Chronic disease name is usually first diagnosed among middle age patients. African Americans have a higher frequency of developing Lupus nephritis in the United States.
Epidemiology and Demographics
Incidence
- The incidence of lupus nephritis is different among:[1]
Blacks: 34 to 51 percent
Hispanics: 31 to 43 percent
Asians: 33 to 55 percent
Whites: 14 to 23 percent
- In 2005, Incidence was fiund to be 5.1 (Overall), 1.9 (Adult men), 8.2 (Adult women)[1]
Prevalence
| Systemic Lupus Erythematosus (per 100,000)[2] | |
|---|---|
| North America[3] | 4.8 to 78.5 |
| Europe[3] | 25 to 91 |
| Australia[3] | 19 to 63 |
| Japan[3] | 8 to 18 |
| China[3] | 30 to 50 |
Case-fatality rate/Mortality rate
- The overall mortality rate of lupus is very high, estimated to have approximately 50,000 deaths per 100,000 cases.
Age
- Patients of all age groups may develop Lupus nephritis.[3]
- The incidence of Lupus nephritis increases with age upto 50 years; the median age at diagnosis is 25 years.[3]
- Lupus nephritis commonly affects individuals older than 18 years of age.
- Chronic disease name is usually first diagnosed among middle age patients.[3]
- Acute disease commonly affects young females.
Race
- In 1995, the incidence of SLE was estimated to be 2.0 in White adults, 0.4 in White men, 3.5 in White women, 5.3 in African American adults, and 0.7 African America men.[1]
Gender
- Females are more commonly affected with Lupus nephritis. With an overall female to male ratio of approximately 8:1 in adults and 4:3 in children.[3]
Race
- African Americans have a higher frequency of developing Lupus nephritis in the United States.[3]
| Frequency rate %[2] | |
|---|---|
| Caucasian | 29 |
| Asian | 40-82 |
| Hispanic | 61 |
| Black | 69 |
References
- ↑ 1.0 1.1 1.2 Feldman CH, Hiraki LT, Liu J, Fischer MA, Solomon DH, Alarcón GS, Winkelmayer WC, Costenbader KH (March 2013). "Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004". Arthritis Rheum. 65 (3): 753–63. doi:10.1002/art.37795. PMC 3733212. PMID 23203603.
- ↑ 2.0 2.1 Almaani S, Meara A, Rovin BH (2017). "Update on Lupus Nephritis". Clin J Am Soc Nephrol. 12 (5): 825–835. doi:10.2215/CJN.05780616. PMID 27821390.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 3.9 Danchenko N, Satia JA, Anthony MS (2006). "Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden". Lupus. 15 (5): 308–18. doi:10.1191/0961203306lu2305xx. PMID 16761508 PMID: 16761508 Check
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