Levophenacylmorphan

Levophenacylmorphan
Clinical data
Synonyms	Levophenacylmorphan
Legal status
Legal status	US: Schedule I ;
Identifiers
	IUPAC name (-)-3-Hydroxy-N-phenacylmorphinan;
CAS Number	10061-32-2;
PubChem CID	5362482;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C24H27NO2
Molar mass	361.48 g/mol
3D model (JSmol)	Interactive image;
	SMILES C1CC[C@@]23CCN([C@@H]([C@@H]2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5;

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Levophenacylmorphan is a morphinan derivative that acts as an opioid agonist. It has potent analgesic effects and is around 10x more potent than morphine.^[1] It also produces all the normal opioid side effects such as itching, nausea, respiratory depression, and development of tolerance and dependence to its effects.^[2]

References

↑ MAY, E.L. & EDDY, N.B., A New Potent Synthetic Analgesic, J. Org. Chem., 24 : 294, 1959.
↑ Fraser HF, Isbell H. Human pharmacology and addiction liabilities of phenazocine and levophenacylmorphan. UN Bulletin on Narcotics. 1960 Issue 2

Template:Opioids

Template:WikiDoc Sources

[1] MAY, E.L. & EDDY, N.B., A New Potent Synthetic Analgesic, J. Org. Chem., 24 : 294, 1959.

[2] Fraser HF, Isbell H. Human pharmacology and addiction liabilities of phenazocine and levophenacylmorphan. UN Bulletin on Narcotics. 1960 Issue 2

[1]

[2]

Levophenacylmorphan

Overview

References

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