Intraductal papilloma

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Intraductal papilloma
Classification and external resources
Histopathology of intraductal papilloma of the breast by excisional biopsy. Immunostaining for p63 protein.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Intraductal papillomas of the breast are relatively common benign lesions with an incidence of approximately 2-3% in humans.[1] They are the most common cause of bloody nipple discharge in women age 20-40 and generally do not show up on mammography due to their small size, so the next step in treatment would be a galactogram to guide the subsequent biopsy.The masses are often too small to be palpated or felt. A galactogram is therefore necessary to rule out the lesion. Excision is sometimes performed as the method of treatment.[2]

Additional Images


  1. Cilotti A, Bagnolesi P, Napoli V, Lencioni R, Bartolozzi C (1991). "[Solitary intraductal papilloma of the breast. An echographic study of 12 cases]". La Radiologia Medica (in Italian). 82 (5): 617–20. PMID 1780459. Unknown parameter |month= ignored (help)
  2. Ahmadiyeh N, Stoleru MA, Raza S, Lester SC, Golshan M (2009). "Management of intraductal papillomas of the breast: an analysis of 129 cases and their outcome". Ann. Surg. Oncol. 16 (8): 2264–9. doi:10.1245/s10434-009-0534-1. PMID 19484312. Unknown parameter |month= ignored (help)

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