HLA-B42
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major histocompatibility complex (human), class I, B42
| ||
| Alleles | B*4201 B*4202 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*4201 | |
| EBI-HLA | B*4202 | |
| Locus | chr.6 6p21.31 | |
HLA-B42 (B42) is an HLA-B serotype. The serotype identifies the HLA-B*4201 and *4202 gene products.[1] HLA-B*4201 is common Central Africa. (For terminology help see: HLA-serotype tutorial)
Serotype
| B*42 | B42 | other | Sample |
| allele | % | % | size (N) |
| 4201 | 93 | 2 | 1015 |
| 4202 | 95 | 80 |
Serological typing for B*4201 and B*4202 is relatively efficient.
B*4201 allele frequencies
| freq | ||
| ref. | Population | (%) |
| [3] | Zambia Lusaka | 14.8 |
| [3] | Mali Bandiagara | 13.8 |
| [3] | Burkina Faso Mossi | 13.2 |
| [3] | South Africian Natal Zulu | 12.0 |
| [3] | Burkina Faso Rimaibe | 9.6 |
| [3] | South Africa Tswana | 8.5 |
| [3] | Kenya Luo | 7.7 |
| [3] | Kenya | 7.3 |
| [3] | Kenya Nandi | 6.9 |
| [3] | Zimbabwe Harare Shona | 6.9 |
| [3] | Saudi Arabia | 5.6 |
| [3] | Cameroon Yaounde | 4.9 |
| [3] | Cameroon Beti | 4.0 |
| [3] | Cameroon Bamileke | 3.9 |
| [3] | Cameroon Sawa | 3.8 |
| [3] | Ivory Coast Akan Adiopodoume | 3.4 |
| [3] | Israel Gaza Palestinians | 2.4 |
| [3] | India North Delhi | 2.2 |
| [3] | Senegal Niokholo Mandenka | 1.6 |
| [3] | Mbenzele Pygmy (C. Afr. Rep.) | 1.5 |
| [3] | Iran Baloch | 1.5 |
| [3] | Pakistan Baloch | 1.5 |
| [3] | Sudanese | 1.5 |
| [3] | Tunisia | 1.5 |
| [3] | Pakistan Brahui | 1.4 |
| [3] | Cameroon Bamileke | 1.3 |
| [3] | Oman | 1.3 |
| [3] | Sudanese | 1.3 |
| [3] | Tunisia Tunis | 1.1 |
| [3] | Zimbabwe Harare Shona | 1.1 |
| [3] | Cameroon Bakola Pygmy | 1.0 |
| [3] | Pakistan Pathan | 1.0 |
| [3] | Portugal Centre | 1.0 |
| [3] | Saudi Arabia Guraiat and Hail | 1.0 |
| [3] | Morocco Casablanca | 0.9 |
| [3] | Senegal Dakar | 0.9 |
| [3] | Uganda Kampala | 0.9 |
| [3] | Cape Verde Southeastern Islands | 0.8 |
| [3] | Guinea Bissau | 0.8 |
| [3] | United Arab Emerates | 0.8 |
| [3] | Morocco Nador Metalsa Class I | 0.7 |
| [3] | Pakistan Karachi Parsi | 0.6 |
| [3] | Spain Majorca | 0.6 |
| [3] | China Yunnan Han pop2 | 0.5 |
| [3] | England Newcastle | 0.5 |
| [3] | Israel Arab Druse | 0.5 |
| [3] | Israel Jews | 0.5 |
| [3] | Italy Rome | 0.5 |
| [3] | Guadalajara Mestizos (2) (Mexico) | 0.5 |
| [3] | Morocco | 0.5 |
| [3] | Pakistan Sindhi | 0.5 |
| [3] | Senegal Niokholo Mandenka | 0.5 |
| [3] | Singapore Riau Malay | 0.5 |
References
- ↑ Marsh SG, Albert ED, Bodmer WF; et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
- ↑ derived from IMGT/HLA
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 3.22 3.23 3.24 3.25 3.26 3.27 3.28 3.29 3.30 3.31 3.32 3.33 3.34 3.35 3.36 3.37 3.38 3.39 3.40 3.41 3.42 3.43 3.44 3.45 3.46 3.47 3.48 3.49 3.50 3.51 3.52 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. PMID 12753660. External link in
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