Genital ulcer

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Genital ulcer
Genital ulcer in an immunsupressed patient
ICD-10 GroupMajor.minor
ICD-9 xxx
DiseasesDB 19297

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List of terms related to Genital ulcer

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-In-Chief: John Fani Srour, M.D.


A Genital ulcer is an ulcer located on the genital area, caused by a sexually transmitted disease such as genital herpes, syphilis, chancroid, or thrush. Some other signs of having genital ulcers include enlarged lymph nodes in the groin area, or vesicular lesions, which are small, elevated sores or blisters. The syndrome may be further classified into penile ulceration and vulval ulceration for males and females respectively.


Common Causes

Other Causes (rare)

Complete Differential Diagnosis of the Causes of Genital Ulcers:

(By organ system)

Cardiovascular No underlying causes
Chemical / poisoning No underlying causes
Dermatologic Balanitis, Behcet's disease, Cancer, Basal cell carcinoma, Squamous cell carcinoma, Chancroid, Chlamydia trachomatis, Herpes Genitalis, Lichen planus, Pyoderma, Syphilis, Cicatricial pemphigoid, Erythema multiforme, Excoriations, Fixed drug eruption, Granuloma inguinale, Langerhans cell histiocytosis, Lymphogranuloma venereum, Pemphigus vulgaris, Reiter's syndrome, Scabies, Stevens-Johnson syndrome, Strachan's syndrome
Drug Side Effect Foscarnet
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic No underlying causes
Iatrogenic Excoriations
Infectious Disease Chancroid, Chlamydia trachomatis, Herpes Genitalis, Human papilloma virus, Neisseria gonorrhoeae, Syphilis (primary syphilis), Vulvovaginitis, Cytomegalovirus infection, Granuloma inguinale,

Lymphogranuloma venereum, Scabies, Yeast infection, HIV, Klebsiella granulomatis, EBV infection

Musculoskeletal / Ortho No underlying causes
Neurologic No underlying causes
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic skin cancer, basal cell carcinoma, squamous cell carcinoma, Langerhans cell histiocytosis
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Behcet's disease, Athabaskan severe combined immunodeficiency, Cicatricial pemphigoid, Erythema multiforme, Fixed drug eruption, Pemphigus vulgaris, Reiter's syndrome, Stevens-Johnson syndrome
Sexual No underlying causes
Trauma Genital trauma, Excoriations
Urologic Balanitis, Cancer, Chancroid, Genital trauma, Granuloma inguinale, Lymphogranuloma venereum, Yeast infection
Miscellaneous No underlying causes

Medical Therapy

Pathogen-Based Therapy


  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
  3. Martín JM, Pinazo I, Molina I; et al. (2009). "Cicatricial pemphigoid of the Brunsting-Perry type". Int. J. Dermatol. 48 (3): 293–4. doi:10.1111/j.1365-4632.2009.03975.x. PMID 19261020. Unknown parameter |month= ignored (help)
  4. Fischer G (2007). "Vulvar fixed drug eruption. A report of 13 cases". J Reprod Med. 52 (2): 81–6. PMID 17393766. Unknown parameter |month= ignored (help)
  5. Luelmo J, Sala M, Sasal M, Cervantes M (1996). "[Genital ulcers from foscarnet: three cases]". Med Clin (Barc) (in Spanish; Castilian). 107 (8): 318. PMID 8965499. Unknown parameter |month= ignored (help)
  6. Cockerell OC, Ormerod IE (1993). "Strachan's syndrome: variation on a theme". J. Neurol. 240 (5): 315–8. PMID 8326339. Unknown parameter |month= ignored (help)

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