Epilepsy natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
If left untreated, 23% to 71% of patients with a single unprovoked seizure may experience it again within 2 years. After the second unprovoked seizure, the chance of having another seizure increase to 73%. Recurrent seizures with no underlying illness emphasis on epilepsy diagnosis. Common complications of epilepsy include: Status epilepticus, sudden unexpected death, submersion Injury, dental injury, burns, fractures, head injury, soft tissue injury and motor vehicle accidents.
Natural History, Complications, and Prognosis
Natural History
- If left untreated, 23% to 71% of patients with a single unprovoked seizure may experience it again within 2 years.
- After the second unprovoked seizure, the chance of having another seizure increase to 73%.
- Recurrent seizures with no underlying illness emphasis on epilepsy diagnosis.
- In contrast to adolescent onset epilepsy syndromes most of the childhood onset epilepsy such as benign childhood epilepsy with centrotemporal spikes will go to remission.
- There is no evidence demonstrating the effect of medical therapy on natural history of epilepsy.[1]
Complications
- Common complications of epilepsy include:
- Status epilepticus[2]
- Sudden unexpected death[3]
- Submersion Injury
- Dental injury[4]
- Burns[5]
- Fractures[6]
- Head injury
- Soft tissue injury[7]
- Motor vehicle accidents[8]
- Epileptic heart[9]
- Sudden cardiac death
References
- ↑ Samuels, Martin (2017). Samuels's Manual of neurologic therapeutics. Philadelphia: Wolters Kluwer Health. ISBN 9781496360311.
- ↑ Mattle, Heinrich (2017). Fundamentals of neurology : an illustrated guide. Stuttgart New York: Thieme. ISBN 9783131364524.
- ↑ Samuels, Martin (2017). Samuels's Manual of neurologic therapeutics. Philadelphia: Wolters Kluwer Health. ISBN 9781496360311.
- ↑ Buck D, Baker GA, Jacoby A, Smith DF, Chadwick DW (April 1997). "Patients' experiences of injury as a result of epilepsy". Epilepsia. 38 (4): 439–44. PMID 9118849.
- ↑ van den Broek M, Beghi E (January 2004). "Morbidity in patients with epilepsy: type and complications: a European cohort study". Epilepsia. 45 (1): 71–6. PMID 14692910.
- ↑ Pack AM, Olarte LS, Morrell MJ, Flaster E, Resor SR, Shane E (April 2003). "Bone mineral density in an outpatient population receiving enzyme-inducing antiepileptic drugs". Epilepsy Behav. 4 (2): 169–74. PMID 12697142.
- ↑ Beghi E, Cornaggia C (September 2002). "Morbidity and accidents in patients with epilepsy: results of a European cohort study". Epilepsia. 43 (9): 1076–83. PMID 12199734.
- ↑ Hansotia P, Broste SK (1993). "Epilepsy and traffic safety". Epilepsia. 34 (5): 852–8. PMID 8404737.
- ↑ Verrier, Richard L.; Pang, Trudy D.; Nearing, Bruce D.; Schachter, Steven C. (2020). "The Epileptic Heart: Concept and clinical evidence". Epilepsy & Behavior. 105: 106946. doi:10.1016/j.yebeh.2020.106946. ISSN 1525-5050.