Encephalopathy screening

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Encephalopathy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

Screening helps in identification of impending encephalopathy or detection of subclinical encephalopathy. Presently strategies for detecting subclinical hepatic encephalopathy[1] and neonatal encephalopathy[2] due to raised bilirubin levels exist.

Screening

Subclinical Hepatic Encephalopathy

Psychometric assessment, automated analysis of EEG and sickness impact profile can be used to diagnose subclinical encephalopathy. Combined evaluation of results of these tests helps in detecting subclinical encephalopathy.[1]

Bilirubin Encephalopathy

A single test or study is not effective in detecting the bilirubin encephalopathy. Based on retrospective analyses among infants who had both early and late total serum bilirubin (TSB) measurements available, the combination of risk factors and early TSB measurement has better diagnostic ability to predict clinically significant hyperbilirubinemia compared to risk factors alone.[3]

References

  1. 1.0 1.1 Groeneweg M, Moerland W, Quero JC, Hop WC, Krabbe PF, Schalm SW (2000). "Screening of subclinical hepatic encephalopathy". J. Hepatol. 32 (5): 748–53. PMID 10845661. Unknown parameter |month= ignored (help)
  2. http://www.ncbi.nlm.nih.gov/books/NBK34036/
  3. http://www.ncbi.nlm.nih.gov/books/NBK34036/

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