Duodenal cytochrome B
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| cytochrome b reductase 1 | |
|---|---|
| Identifiers | |
| Symbol | CYBRD1 |
| Alt. symbols | DCYTB |
| Entrez | 79901 |
| HUGO | 20797 |
| OMIM | 605745 |
| RefSeq | NM_024843 |
| UniProt | Q53TN4 |
| Other data | |
| Locus | Chr. 2 q31 |
Duodenal cytochrome B (Dcytb) has been identified as the reductase enzyme which catalyzes the reduction of Fe3+ to Fe2+ in the process of iron absorption in the duodenum of mammals.[1] According to research carried out, it appears that Dcytb upregulation is controlled by a number of independent stimulators or inhibitors of iron absorption. Furthermore, Dcytb has also been shown to exist in other tissues besides the apical region of the duodenum; and as such, it is believed to play a major role in iron metabolism in tissues.
References
- ↑ Latunde-Dada GO, Van der Westhuizen J, Vulpe CD, et al. (2002). "Molecular and functional roles of duodenal cytochrome B (Dcytb) in iron metabolism". Blood Cells Mol. Dis. 29 (3): 356–60. doi:10.1006/bcmd.2002.0574. PMID 12547225.
External links
- duodenal+cytochrome+b,+human at the US National Library of Medicine Medical Subject Headings (MeSH)