Doxycycline hyclate
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Doxycycline (IPA is a tetracycline antibiotic which is commonly used to treat a variety of infections. Doxycycline product received Food and Drug Administration (United States)|US Food and Drug Administration approval in 1967.[1] Other brand names include Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx,[2] Vibrox, Adoxa, Doxyhexal, Doxylin, Doxoral, Doxy-1 and Atridox (topical doxycycline hyclate for periodontitis).
Category
US Brand Names
DOXY 100®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Doxycycline is primarily bacteriostatic and thought to exert its antimicrobial effect by the inhibition of protein synthesis. it acts by binding to the 30S and 50S ribosomal subunits, which impairs protein synthesis by bacteria. Doxycycline is active against a wide range of gram-positive and gram-negative organisms.[3]
References
- ↑ "Vibramycin. HUMAN PRESCRIPTION DRUG LABEL". DailyMed. U.S. National Library of Medicine. Retrieved 3 October 2013.
- ↑ Voreacos, David; Decker, Susan (30 April 2012). "Mylan, Impax Win Ruling in Doryx Generics Patent Case". Bloomberg.
- ↑ "DOXY 100 (DOXYCYCLINE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [APP PHARMACEUTICALS, LLC]". Text " accessdate" ignored (help)