Co-tenidone

Co-tenidone

Combination of
Atenolol	Beta blocker
Chlortalidone	Thiazide diuretic
[[{{{component3}}}]]	? Class
[[{{{component4}}}]]	? Class
[[{{{component5}}}]]	? Class
[[{{{component6}}}]]	? Class
Gene therapy
Clinical data
Routes of administration	Oral
Physiological data
Legal status
Legal status	UK: POM (Prescription only)
Pharmacokinetic data
Identifiers
Chemical and physical data

Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line as they perform less well than other drugs, and that atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes.

Formulation

Two strengths of co-amilozide is currently available in the UK:

• 50 mg atenolol and 12.5 mg chlortalidone , BAN of Co-tenidone 50/12.5
• 100 mg atenolol and 25 mg chlortalidone , BAN of Co-tenidone 100/25

References

• British National Formulary 54 September 2007