Endothelin receptor antagonist
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. 
A endothelin receptor antagonist (ERA) is a drug which blocks endothelin receptors.
Two main kinds of ERAs exist:
- selective ERA (e.g. sitaxsentan), which affect endothelin A.
- dual ERAs,(e.g. bosentan) which affect both endothelin A and B .