Co-amilozide

Co-amilozide

Combination of
Amiloride	Potassium-sparing diuretic
Hydrochlorothiazide	Thiazide diuretic
[[{{{component3}}}]]	? Class
[[{{{component4}}}]]	? Class
[[{{{component5}}}]]	? Class
[[{{{component6}}}]]	? Class
Gene therapy
Clinical data
Routes of administration	Oral
ATC code	C03EA01 (WHO)
Physiological data
Legal status
Legal status	UK: POM (Prescription only)
Pharmacokinetic data
Identifiers
Chemical and physical data

Co-amilozide (BAN) is a non-proprietary name used to denote a combination of amiloride and hydrochlorothiazide. Co-amilozide is used in the treatment of hypertension and congestive heart failure with the tendency of the thiazide to cause low potassium levels (hypokalaemia) offset by the potassium-sparing effects of amiloride.

Formulation

Two strengths of co-amilozide is currently available in the UK:

• 2.5 mg amiloride and 25 mg hydrochlorothiazide, BAN of Co-amilozide 2.5/25 (brand name Moduretic 25)
• 5 mg amiloride and 50 mg hydrochlorothiazide, BAN of Co-amilozide 5/50 (brand name Moduretic)

References

• British National Formulary 54 September 2007