Iridocorneal endothelial syndrome

(Redirected from Chandler's syndrome)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Jyostna Chouturi, M.B.B.S [2]


Iridocorneal endothelial or ICE syndrome is a spectrum of conditions of the eye,[1] where the inner layer of the cornea appears abnormal.[2] It includes Cogan-Reese syndrome, Chandler's syndrome, and progressive iris atrophy.

Historical Prospective

"Cogan-Reese syndrome" is named for David Glendenning Cogan and Algernon Reese.[3][4]


  1. Lefebvre V, Sowka JW, Frauens BJ (August 2009). "The clinical spectrum between posterior polymorphous dystrophy and iridocorneal endothelial syndromes". Optometry. 80 (8): 431–6. doi:10.1016/j.optm.2009.02.009. PMID 19635434.
  2. Mastering the Techniques of Glaucoma Diagnosis and Management. Jaypee Brothers Medical Publishers (P) Ltd. 2006. ISBN 81-8061-758-0.
  3. Template:WhoNamedIt
  4. Cogan DG, Reese AB (1969). "A syndrome of iris nodules, ectopic Descemet's membrane, and unilateral glaucoma". Doc Ophthalmol. 26: 424–33. doi:10.1007/bf03186675. PMID 5359536.

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