Breast lumps screening
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Risk calculators and risk factors for Breast lumps screening
Editor-In-Chief: C. Michael Gibson, M.S., M.D. ; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.
Screening for breast lumps is recommended by breast examination, ultrasound, mammography, magnetic resonance imaging.
The Screening methods of breast lesions:
- Breast examination
- Self breast examination
- Although this is controversial, most clinicians recommend women to perform self examination monthly.
- Clinical breast examination
- Women with age> 40 years is recommended to have clinical breast examination, annually.
- Self breast examination
- Whole breast ultrasound detects lesions in dense breast tissue which could not be diagnosed by mammography.
- Gold standard test of screening
- Early detection of non-palpabale masses
- According to 2013 NCCN guidelines
- Annual screening in average risk women aged ≥ 40 years
- Annual screening in high risk women from age of 25 years
- Sensitivity of 0.33-0.39 and specificity of 0.95
- Magnetic resonance imaging
- Significant method for detection, assessment, and management of breast cancer
- Sensitivity of 0.77-0.79 and specificity of 0.86-0.89
- According on 2013 NCCN guidelines
- Annual MRI for individuals with > 20% risk of developing breast cancer in lifetime starting at age of 25 years
- Beneficial modality for screening in high risk individuals
- Valuable screening method in individuals with equivocal results from other screening tests
- Usable for individuals with ineffective mammography results due to breast augmentation
- ↑ Shah R, Rosso K, Nathanson SD (2014). "Pathogenesis, prevention, diagnosis and treatment of breast cancer". World J Clin Oncol. 5 (3): 283–98. doi:10.5306/wjco.v5.i3.283. PMC 4127601. PMID 25114845.
- ↑ Kelly KM, Dean J, Comulada WS, Lee SJ (2010). "Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense breasts". Eur Radiol. 20 (3): 734–42. doi:10.1007/s00330-009-1588-y. PMC 2822222. PMID 19727744.
- ↑ 3.0 3.1 Kriege M, Brekelmans CT, Boetes C, Besnard PE, Zonderland HM, Obdeijn IM; et al. (2004). "Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition". N Engl J Med. 351 (5): 427–37. doi:10.1056/NEJMoa031759. PMID 15282350. Review in: ACP J Club. 2005 Jan-Feb;142(1):23
- ↑ Warner E, Messersmith H, Causer P, Eisen A, Shumak R, Plewes D (2008). "Systematic review: using magnetic resonance imaging to screen women at high risk for breast cancer". Ann Intern Med. 148 (9): 671–9. PMID 18458280.