Benzylthiouracil

	WikiDoc Resources for Benzylthiouracil
Articles
Most recent articles on Benzylthiouracil Most cited articles on Benzylthiouracil Review articles on Benzylthiouracil Articles on Benzylthiouracil in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Benzylthiouracil Images of Benzylthiouracil Photos of Benzylthiouracil Podcasts & MP3s on Benzylthiouracil Videos on Benzylthiouracil
Evidence Based Medicine
Cochrane Collaboration on Benzylthiouracil Bandolier on Benzylthiouracil TRIP on Benzylthiouracil
Clinical Trials
Ongoing Trials on Benzylthiouracil at Clinical Trials.gov Trial results on Benzylthiouracil Clinical Trials on Benzylthiouracil at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Benzylthiouracil NICE Guidance on Benzylthiouracil NHS PRODIGY Guidance FDA on Benzylthiouracil CDC on Benzylthiouracil
Books
Books on Benzylthiouracil
News
Benzylthiouracil in the news Be alerted to news on Benzylthiouracil News trends on Benzylthiouracil
Commentary
Blogs on Benzylthiouracil
Definitions
Definitions of Benzylthiouracil
Patient Resources / Community
Patient resources on Benzylthiouracil Discussion groups on Benzylthiouracil Patient Handouts on Benzylthiouracil Directions to Hospitals Treating Benzylthiouracil Risk calculators and risk factors for Benzylthiouracil
Healthcare Provider Resources
Symptoms of Benzylthiouracil Causes & Risk Factors for Benzylthiouracil Diagnostic studies for Benzylthiouracil Treatment of Benzylthiouracil
Continuing Medical Education (CME)
CME Programs on Benzylthiouracil
International
Benzylthiouracil en Espanol Benzylthiouracil en Francais
Business
Benzylthiouracil in the Marketplace Patents on Benzylthiouracil
Experimental / Informatics
List of terms related to Benzylthiouracil

Benzylthiouracil
Clinical data
Routes of; administration	Oral
ATC code	H03BA03 (WHO) ;
Pharmacokinetic data
Excretion	Renal
Identifiers
	IUPAC name 1-(1-cyclohexa-2,4-dienylmethyl)-7-thia-; 3,5-diazabicyclo[4.1.0]hepta-3,5-dien-2-one;
CAS Number	6336-50-1;
PubChem CID	685814;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C11H10N2OS
Molar mass	218.276 g/mol

Benzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.

Adverse effects

Benzylthiouracil has been associated with severe adverse effects, notably vasculitis and subsequent ANCA-positive glomerulonephritis, as well as isolated reports of lung damage.^[1]^[2]^[3]^[4]

References

↑ Tieulie N, Huong DL, Andreu M; et al. (2002). "[ANCA associated glomerulonephritis related to benzylthiouracil]". Rev Med Interne (in French). 23 (10): 853–6. PMID 12428489.
↑ Kaaroud H, Khiari K, Ben Moussa F, Barbouch S, Boussema E, Ben Maïz H (2002). "[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease]". Rev Med Interne (in French). 23 (10): 857–61. PMID 12428490.
↑ Braham A, Houman MH, Rais L, Ben Gborbel I, Lamloum M, Miled M (2004). "[Benzylthiouracil induced ANCA-positive vasculitis]". Presse médicale (in French). 33 (19 Pt 1): 1331–3. PMID 15615240.
↑ Thabet F, Sghiri R, Tabarki B, Ghedira I, Yacoub M, Essoussi AS (2006). "ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil". Eur J Pediatr. 165 (7): 435–6. doi:10.1007/s00431-005-0053-4. PMID 16622664.

Template:Thyroid therapy

Template:WikiDoc Sources

[1] Tieulie N, Huong DL, Andreu M; et al. (2002). "[ANCA associated glomerulonephritis related to benzylthiouracil]". Rev Med Interne (in French). 23 (10): 853–6. PMID 12428489.

[2] Kaaroud H, Khiari K, Ben Moussa F, Barbouch S, Boussema E, Ben Maïz H (2002). "[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease]". Rev Med Interne (in French). 23 (10): 857–61. PMID 12428490.

[3] Braham A, Houman MH, Rais L, Ben Gborbel I, Lamloum M, Miled M (2004). "[Benzylthiouracil induced ANCA-positive vasculitis]". Presse médicale (in French). 33 (19 Pt 1): 1331–3. PMID 15615240.

[4] Thabet F, Sghiri R, Tabarki B, Ghedira I, Yacoub M, Essoussi AS (2006). "ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil". Eur J Pediatr. 165 (7): 435–6. doi:10.1007/s00431-005-0053-4. PMID 16622664.

[1]

[2]

[3]

[4]

Clinical data

Routes of administration	Oral
ATC code	H03BA03 (WHO)
Pharmacokinetic data
Excretion	Renal
Identifiers
IUPAC name 1-(1-cyclohexa-2,4-dienylmethyl)-7-thia- 3,5-diazabicyclo[4.1.0]hepta-3,5-dien-2-one
CAS Number	6336-50-1
PubChem CID	685814
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₁H₁₀N₂OS
Molar mass	218.276 g/mol

Benzylthiouracil

Adverse effects

References

Navigation menu

Search