Behçet's disease risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
Common risk factors in the development of Behcet disease may be occupational, environmental, genetic, and viral. Behçet's disease can affect people in any age, but the most common age is 20~30 years old. Behçet's disease is more common in Middle East and Japan then in other race. It is rare in America. Researches demonstrate that the presence of the gene HLA–B51 is a risk factor for Behçet's disease.
Risk Factors
The underlying cause of Behçet’s disease is not clear. It is suggested that the following factors may be associated with the disease:
- Genetic predisposition: Researches demonstrate that the presence of the gene HLA–B51 is a risk factor for Behçet's disease.[1][2]
- Age: Behçet's disease can affect people in any age, but the most common age is 20~30 years old.
- Gender: Behçet's disease most commonly affects men than women.
- Race: Behçet's disease is more common in Middle East and Japan then in other race. It is rare in America.[3]
References
- ↑ Treudler R, Orfanos CE, Zouboulis CC (1999). "Twenty-eight cases of juvenile-onset Adamantiades-Behçet disease in Germany". Dermatology. 199 (1): 15–9. doi:10.1159/000018197. PMID 10449951.
- ↑ Soy M, Erken E, Konca K, Ozbek S (2000). "Smoking and Behçet's disease". Clin Rheumatol. 19 (6): 508–9. PMID 11147770.
- ↑ Yazici H, Fresko I, Yurdakul S (2007). "Behçet's syndrome: disease manifestations, management, and advances in treatment". Nat Clin Pract Rheumatol. 3 (3): 148–55. doi:10.1038/ncprheum0436. PMID 17334337.