Alprenolol

Alprenolol

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	C07AA01 (WHO)
Pharmacokinetic data
Protein binding	80% - 90%
Elimination half-life	2-3 hours → 4-OH-alprenolol
Identifiers
IUPAC name (RS)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol
CAS Number	13655-52-2 Y
PubChem CID	2119
IUPHAR/BPS	563
DrugBank	DB00866 Y
ChemSpider	2035 Y
UNII	877K5MQ27W
KEGG	D07156 Y
ChEBI	CHEBI:51211 Y
ChEMBL	ChEMBL266195 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C15H23NO2
Molar mass	249.34 g/mol
3D model (JSmol)	Interactive image
SMILES O(c1ccccc1C\C=C)CC(O)CNC(C)C
InChI InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3 Y Key:PAZJSJFMUHDSTF-UHFFFAOYSA-N Y
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]

Synonyms / Brand Names: Atenenol (Tsuruhara Seiyaku, Japan); Elp (Shyh Dar, Taiwan); Skajilol (Kotobuki Seiyaku, Japan)

Overview

Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as 5-HT_1A receptor antagonist, used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.