Akinesia
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Ongoing Trials on Akinesia at Clinical Trials.gov Clinical Trials on Akinesia at Google
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US National Guidelines Clearinghouse on Akinesia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Akinesia (from the prefix a-, "without", and the Greek κίνηση, kinisi, "motion") is the inability to initiate movement due to difficulty selecting and/or activating motor programs in the central nervous system. Common in severe cases of Parkinson's disease, akinesia is a result of severely diminished dopaminergic cell activity in the direct pathway of movement.
Drug Side Effect
Akinetic Mutism
Akinetic mutism is a condition in which a person is both mute and akinetic. A textbook on clinical neurology observes that a person with akinetic mutism has "sleep-waking cycles but, when apparently awake, with eyes open, lies mute, immobile and unresponsive." Some dictionaries describe it as "loss of normal muscle tone."