Acetyldigoxin

Acetyldigoxin

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	C01AA02 (WHO)
Pharmacokinetic data
Bioavailability	90%(Oral)
Protein binding	20-30%
Elimination half-life	40h
Identifiers
IUPAC name [6-[6-[ [6-[ [12,14-dihydroxy-10,13-dimethyl-17-
CAS Number	5511-98-8
PubChem CID	11765960
ChemSpider	9940650 Y
UNII	P7K44M64CW
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C43H66O15
Molar mass	822.975 g/mol
3D model (JSmol)	Interactive image
SMILES O=C\1OC/C(=C/1)[C@H]2CC[C@@]8(O)[C@]2(C)[C@H](O)C[C@H]7[C@H]8CC[C@H]6[C@]7(C)CC[C@H](O[C@@H]5O[C@H](C)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]3O[C@@H]([C@@H](O)[C@@H](OC(=O)C)C3)C)[C@@H](O)C4)C)[C@@H](O) C5)C6
InChI InChI=1S/C43H66O15/c1-20-38(49)32(55-23(4)44)18-37(52-20)58-40-22(3)54-36(17-31(40)46)57-39-21(2)53-35(16-30(39)45)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(47)42(6)27(10-12-43(28,42)50)24-13-34(48)51-19-24/h13,20-22,25-33,35-40,45-47,49-50H,7-12,14-19H2,1-6H3/t20-,21-,22-,25-,26+,27-,28-,29+,30+,31+,32+,33-,35+,36+,37+,38-,39-,40-,41+,42+,43+/m1/s1 Y Key:HWKJSYYYURVNQU-DXJNJSHLSA-N Y
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acetyldigoxin is a cardiac glycoside. It is an acetyl derivative of digoxin. Its positive cardioinotropic effect starts after 3-4h and maximizes after 6-8h. It is prescribed for congestive chronic cardiac failure class II, III and IV.