AP1GBP1

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AP1 gamma subunit binding protein 1
Identifiers
Symbols AP1GBP1 ; MGC104959; SYNG
External IDs Template:OMIM5 Template:MGI HomoloGene50953
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

AP1 gamma subunit binding protein 1, also known as AP1GBP1, is a human gene.[1]

This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene.[1]

References

  1. 1.0 1.1 "Entrez Gene: AP1GBP1 AP1 gamma subunit binding protein 1".

Further reading

  • Peyrard M, Parveneh S, Lagercrantz S; et al. (1998). "Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG)". Genomics. 50 (2): 275–80. doi:10.1006/geno.1998.5289. PMID 9653655.
  • Page LJ, Sowerby PJ, Lui WW, Robinson MS (1999). "Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin". J. Cell Biol. 146 (5): 993–1004. PMID 10477754.
  • Hirst J, Lui WW, Bright NA; et al. (2000). "A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome". J. Cell Biol. 149 (1): 67–80. PMID 10747088.
  • Fernández-Chacón R, Achiriloaie M, Janz R; et al. (2000). "SCAMP1 function in endocytosis". J. Biol. Chem. 275 (17): 12752–6. PMID 10777571.
  • Takatsu H, Yoshino K, Nakayama K (2000). "Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin". Biochem. Biophys. Res. Commun. 271 (3): 719–25. doi:10.1006/bbrc.2000.2700. PMID 10814529.
  • Nogi T, Shiba Y, Kawasaki M; et al. (2002). "Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain". Nat. Struct. Biol. 9 (7): 527–31. doi:10.1038/nsb808. PMID 12042876.
  • Kent HM, McMahon HT, Evans PR; et al. (2003). "Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin". Structure. 10 (8): 1139–48. PMID 12176391.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Mills IG, Praefcke GJ, Vallis Y; et al. (2003). "EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking". J. Cell Biol. 160 (2): 213–22. doi:10.1083/jcb.200208023. PMID 12538641.
  • Lui WW, Collins BM, Hirst J; et al. (2004). "Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin". Mol. Biol. Cell. 14 (6): 2385–98. doi:10.1091/mbc.E02-11-0735. PMID 12808037.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Hirst J, Borner GH, Harbour M, Robinson MS (2005). "The aftiphilin/p200/gamma-synergin complex". Mol. Biol. Cell. 16 (5): 2554–65. doi:10.1091/mbc.E04-12-1077. PMID 15758025.
  • Theos AC, Tenza D, Martina JA; et al. (2006). "Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes". Mol. Biol. Cell. 16 (11): 5356–72. doi:10.1091/mbc.E05-07-0626. PMID 16162817.

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