Zygomycosis surgery
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Zygomycosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Zygomycosis surgery On the Web |
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American Roentgen Ray Society Images of Zygomycosis surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
Surgery
Surgical therapy can be very drastic, and in some cases of Rhinocerebral disease removal of infected brain tissue may be required. In some cases surgery may be disfiguring because it may involve removal of the palate, nasal cavity, or eye structures.[1] Surgery may be extended to more than one operation.[2] It has been hypothesised that hyperbaric oxygen may be beneficial as an adjunctive therapy because higher oxygen pressure increases the ability of neutrophils to kill the organism.[3]
Treatment for Phycomycosis is very difficult and includes surgery when possible. Postoperative recurrence is common. Antifungal drugs show only limited effect on the disease, but itraconazole and terbinafine hydrochloride are often used for two to three months following surgery.[4] Humans with Basidiobolus infections have been treated with amphotericin B and potassium iodide.[5] For pythiosis and lagenidiosis, a new drug targeting water moulds called caspofungin is available, but it is very expensive.[4] Immunotherapy has been used successfully in humans and horses with pythiosis.[6]
References