Subcutaneous panniculitis-like T-cell lymphoma: Difference between revisions

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==== Other Imaging Findings ====
==== Other Imaging Findings ====
[[PET]] scan may be helpful in the diagnosis of subcutaneous panniculitis-like T-cell lymphoma.
[[PET]] scan may be helpful in the diagnosis of subcutaneous panniculitis-like T-cell lymphoma.
==Treatment==
==Treatment==



Revision as of 15:50, 8 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Synonyms and keywords:

Overview

Pathophysiology

Associated Conditions

Microscopic Pathology

Causes

There are no established causes for subcutaneous panniculitis-like T-cell lymphoma.

Differentiating type page name here from other Diseases

Subcutaneous panniculitis-like T-cell lymphoma must be differentiated from other diseases such as:

Epidemiology and Demographics

Age

The incidence of subcutaneous panniculitis-like T-cell lymphoma increases with age; the median age at diagnosis is 35 years.

Gender

Females are more commonly affected with subcutaneous panniculitis-like T-cell lymphoma than males.

Risk Factors

There are no established risk factors for subcutaneous panniculitis-like T-cell lymphoma.

Screening

According to the the U.S. Preventive Service Task Force (USPSTF), there is insufficient evidence to recommend routine screening for subcutaneous panniculitis-like T-cell lymphoma.[1]

Natural History, Complications and Prognosis

Diagnosis

Staging

Staging for subcutaneous panniculitis-like T-cell lymphoma is provided in the following table:[2]

Revised staging system for primary nodal lymphomas (Lugano classification)
Stage Involvement Extranodal (E) status
Limited
Stage I One node or a group of adjacent nodes Single extranodal lesions without nodal involvement
Stage II Two or more nodal groups on the same side of the diaphragm Stage I or II by nodal extent with limited contiguous extranodal involvement
Stage II bulky II as above with "bulky" disease Not applicable
Advanced
Stage III Nodes on both sides of the diaphragm; nodes above the diaphragm with spleen involvement Not applicable
Stage IV Additional noncontiguous extralymphatic involvement Not applicable

Symptoms

Symptoms of the subcutaneous panniculitis-like T-cell lymphoma include:

Physical Examination

Vitals

Skin

  • Subcutaneous nodules

HEENT

Thorax

Abdomen

Extremities

Laboratory Findings

Laboratory tests for subcutaneous panniculitis-like T-cell lymphoma include:

Biopsy

Lymph node or bone marrow biopsy is diagnostic of subcutaneous panniculitis-like T-cell lymphoma.

CT

CT scan may be helpful in the diagnosis of subcutaneous panniculitis-like T-cell lymphoma.

MRI

MRI scan may be helpful in the diagnosis of subcutaneous panniculitis-like T-cell lymphoma.

Other Imaging Findings

PET scan may be helpful in the diagnosis of subcutaneous panniculitis-like T-cell lymphoma.

Treatment

Medical Therapy

Treatment of subcutaneous panniculitis-like T-cell lymphoma[3]
Therapy Description
Chemotherapy
  • Combination therapy :
Radiation therapy
Stem cell transplant
  • May be used in some people with subcutaneous panniculitis-like T-cell lymphoma when their lymphoma recurs after treatment.

References

  1. Recommendations. U.S Preventive Services Task Force. Accessed on March 8, 2016
  2. Cheson, Bruce D.; Fisher, Richard I.; Barrington, Sally F.; Cavalli, Franco; Schwartz, Lawrence H.; Zucca, Emanuele; Lister, T. Andrew; Alliance, Australasian Leukaemia and Lymphoma Group; Eastern Cooperative Oncology Group; European Mantle Cell Lymphoma Consortium; Italian Lymphoma Foundation; European Organisation for Research; Treatment of Cancer/Dutch Hemato-Oncology Group; Grupo Español de Médula Ósea; German High-Grade Lymphoma Study Group; German Hodgkin's Study Group; Japanese Lymphorra Study Group; Lymphoma Study Association; NCIC Clinical Trials Group; Nordic Lymphoma Study Group; Southwest Oncology Group; United Kingdom National Cancer Research Institute (2014-09-20). "Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification". Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 32 (27): 3059–3068. doi:10.1200/JCO.2013.54.8800. ISSN 1527-7755. PMID 25113753.
  3. Subcutaneous panniculitis-like T-cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/subcutaneous-panniculitis-like-t-cell-lymphoma/?region=nb. Accessed on March 8, 2016