Second degree AV block natural history, complications and prognosis: Difference between revisions

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{{Second degree AV block}}
{{Second degree AV block}}
{{CMG}}; {{AE}} {{RT}}
{{CMG}}; {{AE}} {{Sara.Zand}} {{RT}}


==Overview==
==Overview==
 
[[Second-degree AV nodal block]]  commonly is seen in acute [[clinical]] settings including acute inferior wall [[myocardial infarction]], [[digitalis]] intoxication, [[myocarditis]], [[rheumatic fever]], after [[cardiac]] [[surgery]]. Chronic [[AV nodal block]] is seen in the setting of [[ischemic heart disease]], [[mesothelioma]] of the [[AV node]], [[atrial septal defect]], [[aortic valvular disease]], [[amyloidosis]], [[Reiter's syndrome]], [[mitral valve prolapse]], in [[healthy]] [[populations]], and in [[trained athletes]]. Mobitz II [[second degree Av block]]  due to block inferior to the [[AV node]] ([[infra-Hisian]] structures) may progresses to [[complete heart block]]. Common complications associated with mobitz type 2 [[second degree AV block]] include progression to  [[complete heart block]], [[syncope]], [[dizziness]], [[chest pain]], and [[death]].
Patients with Mobitz type II second degree AV block who are hemodynamically stable do not require urgent therapy with atropine or temporary cardiac pacing. However, Mobitz type II second degree AV block is by nature unstable and frequently progresses to third degree (complete) AV block, so patients should be continuously monitored with transcutaneous pacing pads in place in the event of clinical deterioration. While stable patients are being monitored, reversible causes of Mobitz type II second degree AV block such as myocardial ischemia, increased vagal tone, hypothyroidism, hyperkalemia, and drugs that depress conduction, should be excluded in patients prior to implantation of a permanent pacemaker. For patients with Mobitz type II second degree AV block who do not have a reversible etiology, we recommend implantation of a permanent pacemaker (Grade 1A). We implant a dual chamber DDD pacemaker whenever possible in an effort to maintain physiologic AV synchrony.
Prognosis is generally good in [[patients]] with chronic [[second-degree AV nodal block]] without organic [[heart]] disease.However, in [[patients]] with [[heart ]] [[disease]] prognosis is poor and dependent on the severity of underlying [[heart]] disease.


==Natural History==
==Natural History==
* Mobitz I second degree AV block, usually most of the times, involves the [[AV node]] (70%). In about 30% of the cases the site of block is infranodal. It is usually benign and rarely progresses to [[complete heart block]]<ref name="pmid7471363">{{cite journal |vauthors=Strasberg B, Amat-Y-Leon F, Dhingra RC, Palileo E, Swiryn S, Bauernfeind R, Wyndham C, Rosen KM |title=Natural history of chronic second-degree atrioventricular nodal block |journal=Circulation |volume=63 |issue=5 |pages=1043–9 |date=May 1981 |pmid=7471363 |doi=10.1161/01.cir.63.5.1043 |url=}}</ref>.
* [[Second-degree AV nodal block]]  commonly is seen in acute [[clinical]] settings including acute inferior wall [[myocardial infarction]], [[digitalis]] intoxication, [[myocarditis]], [[rheumatic fever]], or after [[cardiac]] [[surgery]].
* Mobitz II second degree Av block is due to block inferior to the AV node (infra-Hisian structures) and it progresses to complete heart block<ref name="pmid463945">{{cite journal |vauthors=Rodstein M, Wolloch L, Iuster Z |title=The natural history intraventricular conduction disturbances in the aged: an analysis of the developing second and third degree heart block with clinical pathological correlations |journal=Am. J. Med. Sci. |volume=277 |issue=2 |pages=179–88 |date=1979 |pmid=463945 |doi=10.1097/00000441-197903000-00006 |url=}}</ref>.
* Chronic [[AV nodal block]] is seen in the setting of [[ischemic heart disease]], [[mesothelioma]] of the [[AV node]], [[atrial septal defect]], [[aortic valvular disease]],  [[amyloidosis]], [[Reiter's syndrome]], [[mitral valve prolapse]], in [[healthy]] [[populations]] , and in [[trained athletes]].<ref name="pmid7471363">{{cite journal |vauthors=Strasberg B, Amat-Y-Leon F, Dhingra RC, Palileo E, Swiryn S, Bauernfeind R, Wyndham C, Rosen KM |title=Natural history of chronic second-degree atrioventricular nodal block |journal=Circulation |volume=63 |issue=5 |pages=1043–9 |date=May 1981 |pmid=7471363 |doi=10.1161/01.cir.63.5.1043 |url=}}</ref>.
* Mobitz II [[second degree Av block]]  due to block inferior to the [[AV node]] ([[infra-Hisian]] structures) may progresses to [[complete heart block]].<ref name="pmid463945">{{cite journal |vauthors=Rodstein M, Wolloch L, Iuster Z |title=The natural history intraventricular conduction disturbances in the aged: an analysis of the developing second and third degree heart block with clinical pathological correlations |journal=Am. J. Med. Sci. |volume=277 |issue=2 |pages=179–88 |date=1979 |pmid=463945 |doi=10.1097/00000441-197903000-00006 |url=}}</ref>.


==Complications==
==Complications==
::*Common complications associated with [[second degree AV block]] include:
* [[Complete heart block]]<ref name="pmid6373268">{{cite journal |vauthors=Bexton RS, Camm AJ |title=Second degree atrioventricular block |journal=Eur. Heart J. |volume=5 Suppl A |issue= |pages=111–4 |date=March 1984 |pmid=6373268 |doi=10.1093/eurheartj/5.suppl_a.111 |url=}}</ref>
* [[Complete heart block]]<ref name="pmid6373268">{{cite journal |vauthors=Bexton RS, Camm AJ |title=Second degree atrioventricular block |journal=Eur. Heart J. |volume=5 Suppl A |issue= |pages=111–4 |date=March 1984 |pmid=6373268 |doi=10.1093/eurheartj/5.suppl_a.111 |url=}}</ref>
* [[Stokes-Adams syndrome]]
* [[Stokes-Adams syndrome]]
* [[Syncope]]<ref name="pmid29493981">{{cite journal |vauthors=Mangi MA, Jones WM, Napier L |title= |journal= |volume= |issue= |pages= |date= |pmid=29493981 |doi= |url=}}</ref>
* [[Syncope]]<ref name="pmid29493981">{{cite journal |vauthors=Mangi MA, Jones WM, Napier L |title= |journal= |volume= |issue= |pages= |date= |pmid=29493981 |doi= |url=}}</ref>
*Dizziness
*[[Dizziness]]
*Chest pain
*[[Chest pain]]
*Death
*[[Death]]
::* Common complications associated with  [[pacemaker implantation]] can involve:
* [[Pneumothorax]]
* [[Cardiac tamponade]]
* [[Death]]<ref name="pmid8160583">{{cite journal |vauthors=Pfeiffer D, Jung W, Fehske W, Korte T, Manz M, Moosdorf R, Lüderitz B |title=Complications of pacemaker-defibrillator devices: diagnosis and management |journal=Am. Heart J. |volume=127 |issue=4 Pt 2 |pages=1073–80 |date=April 1994 |pmid=8160583 |doi=10.1016/0002-8703(94)90090-6 |url=}}</ref>.
*::After implantation, [[patients]] require generator changes, which carry a particularly high risk of [[infection]] and resultant [[endocarditis]].<ref name="pmid16492298">{{cite journal |vauthors=Bloom H, Heeke B, Leon A, Mera F, Delurgio D, Beshai J, Langberg J |title=Renal insufficiency and the risk of infection from pacemaker or defibrillator surgery |journal=Pacing Clin Electrophysiol |volume=29 |issue=2 |pages=142–5 |date=February 2006 |pmid=16492298 |doi=10.1111/j.1540-8159.2006.00307.x |url=}}</ref>.


==Prognosis==
==Prognosis==
Mobitz type I second degree AV block is usually benign and carries a good prognosis compared to Mobitz type II. But in the setting of an acute [[MI]] [[Mobitz type I]] is associated with a significant rise in mortality.  [[Mobitz II]], as it involves the infra nodal structures, carries the risk of progression to complete heart block and carries an unfavorable prognosis.<ref name="pmid11988196">{{cite journal| author=Meimoun P, Zeghdi R, D'Attelis N, Berrebi A, Braunberger E, Deloche A | display-authors=etal| title=Frequency, predictors, and consequences of atrioventricular block after mitral valve repair. | journal=Am J Cardiol | year= 2002 | volume= 89 | issue= 9 | pages= 1062-6 | pmid=11988196 | doi=10.1016/s0002-9149(02)02276-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11988196  }}</ref>
Prognosis is generally good in [[patients]] with chronic [[second-degree AV nodal block]] without organic [[heart]] disease. However, in [[patients]] with organic [[heart ]] [[disease]] prognosis is poor and dependent on the severity of underlying [[heart]] disease.<ref name="StrasbergAmat-Y-Leon1981">{{cite journal|last1=Strasberg|first1=B|last2=Amat-Y-Leon|first2=F|last3=Dhingra|first3=R C|last4=Palileo|first4=E|last5=Swiryn|first5=S|last6=Bauernfeind|first6=R|last7=Wyndham|first7=C|last8=Rosen|first8=K M|title=Natural history of chronic second-degree atrioventricular nodal block.|journal=Circulation|volume=63|issue=5|year=1981|pages=1043–1049|issn=0009-7322|doi=10.1161/01.CIR.63.5.1043}}</ref>
 
 
 
chronic second-degree AV nodal block has a relatively benign course in patients without organic heart disease. In patients with organic heart disease, prognosis is poor and related to the severity of underlying heart disease.


==References==
==References==

Latest revision as of 04:22, 13 July 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Raviteja Guddeti, M.B.B.S. [3]

Overview

Second-degree AV nodal block commonly is seen in acute clinical settings including acute inferior wall myocardial infarction, digitalis intoxication, myocarditis, rheumatic fever, after cardiac surgery. Chronic AV nodal block is seen in the setting of ischemic heart disease, mesothelioma of the AV node, atrial septal defect, aortic valvular disease, amyloidosis, Reiter's syndrome, mitral valve prolapse, in healthy populations, and in trained athletes. Mobitz II second degree Av block due to block inferior to the AV node (infra-Hisian structures) may progresses to complete heart block. Common complications associated with mobitz type 2 second degree AV block include progression to complete heart block, syncope, dizziness, chest pain, and death. Prognosis is generally good in patients with chronic second-degree AV nodal block without organic heart disease.However, in patients with heart disease prognosis is poor and dependent on the severity of underlying heart disease.

Natural History

Complications

Prognosis

Prognosis is generally good in patients with chronic second-degree AV nodal block without organic heart disease. However, in patients with organic heart disease prognosis is poor and dependent on the severity of underlying heart disease.[7]

References

  1. Strasberg B, Amat-Y-Leon F, Dhingra RC, Palileo E, Swiryn S, Bauernfeind R, Wyndham C, Rosen KM (May 1981). "Natural history of chronic second-degree atrioventricular nodal block". Circulation. 63 (5): 1043–9. doi:10.1161/01.cir.63.5.1043. PMID 7471363.
  2. Rodstein M, Wolloch L, Iuster Z (1979). "The natural history intraventricular conduction disturbances in the aged: an analysis of the developing second and third degree heart block with clinical pathological correlations". Am. J. Med. Sci. 277 (2): 179–88. doi:10.1097/00000441-197903000-00006. PMID 463945.
  3. Bexton RS, Camm AJ (March 1984). "Second degree atrioventricular block". Eur. Heart J. 5 Suppl A: 111–4. doi:10.1093/eurheartj/5.suppl_a.111. PMID 6373268.
  4. Mangi MA, Jones WM, Napier L. PMID 29493981. Missing or empty |title= (help)
  5. Pfeiffer D, Jung W, Fehske W, Korte T, Manz M, Moosdorf R, Lüderitz B (April 1994). "Complications of pacemaker-defibrillator devices: diagnosis and management". Am. Heart J. 127 (4 Pt 2): 1073–80. doi:10.1016/0002-8703(94)90090-6. PMID 8160583.
  6. Bloom H, Heeke B, Leon A, Mera F, Delurgio D, Beshai J, Langberg J (February 2006). "Renal insufficiency and the risk of infection from pacemaker or defibrillator surgery". Pacing Clin Electrophysiol. 29 (2): 142–5. doi:10.1111/j.1540-8159.2006.00307.x. PMID 16492298.
  7. Strasberg, B; Amat-Y-Leon, F; Dhingra, R C; Palileo, E; Swiryn, S; Bauernfeind, R; Wyndham, C; Rosen, K M (1981). "Natural history of chronic second-degree atrioventricular nodal block". Circulation. 63 (5): 1043–1049. doi:10.1161/01.CIR.63.5.1043. ISSN 0009-7322.


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