Sandbox g21
Substrates of Cytochrome P-450 Isozymes
CYP1A2
- Amitriptyline
- Caffeine
- Clomipramine
- Clozapine
- Cyclobenzaprine
- Estradiol
- Fluvoxamine
- Haloperidol
- Mexiletine
- Naproxen
- Olanzapine
- Ondansetron
- Phenacetin
- Propranolol
- Riluzole
- Ropivacaine
- Tacrine
- Theophylline
- Tizanidine
- Verapamil
- R-warfarin
- Zileuton
- Zolmitriptan
CYP2B6
CYP2C8
CYP2C9
- Amitriptyline
- Celecoxib
- Diclofenac
- Fluoxetine
- Fluvastatin
- Glipizide
- Glyburide
- Ibuprofen
- Irbesartan
- Lornoxicam
- Losartan
- Meloxicam
- Nateglinide
- Omeprazole
- Phenytoin
- Piroxicam
- Rosiglitazone
- Rosuvastatin
- S-warfarin
- Tamoxifen
- Tolbutamide
- Torsemide
CYP2C19
- Carisoprodol
- Chloramphenicol
- Citalopram
- Clomipramine
- Cyclophosphamide
- Esomeprazole
- Hexobarbital
- Indomethacin
- Lansoprazole
- Moclobemide
- Nelfinavir
- Nilutamide
- Omeprazole
- Pantoprazole
- Phenobarbital
- Phenytoin
- Primidone
- Progesterone
- Proguanil
- Propranolol
- Rabeprazole
- Teniposide
- Voriconazole
CYP2D6
- Alprenolol
- Amitriptyline
- Amphetamine
- Aripiprazole
- Atomoxetine
- Carvedilol
- Chlorpheniramine
- Chlorpromazine
- Clomipramine
- Codeine
- Debrisoquine
- Desipramine
- Dexfenfluramine
- Dextromethorphan
- Duloxetine
- Encainide
- Flecainide
- Fluoxetine
- Fluvoxamine
- Haloperidol
- Imipramine
- Lidocaine
- Metoclopramide
- Paroxetine
- Perphenazine
- Propafenone
- S-metoprolol
- Thioridazine
- Timolol
CYP2E1
CYP3A
- Alfentanil
- Alprazolam
- Amlodipine
- Aprepitant
- Aripiprazole
- Artemisinin
- Astemizole
- Atazanavir
- Atorvastatin
- Boceprevir
- Buspirone
- Cafergot
- Chlorpheniramine
- Cilostazol
- Clarithromycin
- Cocaine
- Cyclosporine
- Dapsone
- Darunavir
- Dexamethasone
- Dextromethorphan
- Diltiazem
- Docetaxel
- Domperidone
- Eplerenone
- Erythromycin
- Estradiol
- Etravirine
- Felodipine
- Fentanyl
- Finasteride
- Fosamprenavir
- Haloperidol
- Hydrocortisone
- Imatinib
- Indinavir
- Irinotecan
- Lidocaine
- Lovastatin
- Midazolam
- Nateglinide
- Nelfinavir
- Nifedipine
- Nisoldipine
- Nitrendipine
- Ondansetron
- Pimozide
- Progesterone
- Quetiapine
- Quinidine
- Quinine
- Risperidone
- Ritonavir
- Salmeterol
- Saquinavir
- Sildenafil
- Simvastatin
- Sirolimus
- Tacrolimus
- Tadalafil
- Taxol
- Telaprevir
- Telithromycin
- Terfenadine
- Testosterone
- Tipranavir
- Trazodone
- Triazolam
- Troleandomycin
- Vardenafil
- Verapamil
- Vincristine
- Zaleplon
- Ziprasidone
- Zolpidem