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{{See also|Calbindin}}
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
'''[[S100 protein|S100]] calcium-binding protein G''' ('''S100G''') is a [[protein]] that in humans is encoded by the ''S100G'' [[gene]].<ref name="pmid1610358">{{cite journal | vauthors = Howard A, Legon S, Spurr NK, Walters JR | title = Molecular cloning and chromosomal assignment of human calbindin-D9k | journal = Biochem Biophys Res Commun | volume = 185 | issue = 2 | pages = 663–9 | year = 1992 | pmid = 1610358 | pmc =  | doi =10.1016/0006-291X(92)91676-H }}</ref><ref name="pmid1379540">{{cite journal | vauthors = Jeung EB, Krisinger J, Dann JL, Leung PC | title = Molecular cloning of the full-length cDNA encoding the human calbindin-D9k | journal = FEBS Lett | volume = 307 | issue = 2 | pages = 224–8 |date=Sep 1992 | pmid = 1379540 | pmc =  | doi =10.1016/0014-5793(92)80772-9 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: S100G S100 calcium binding protein G| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=795| accessdate = }}</ref>
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = S100 calcium binding protein G
| HGNCid = 1436
| Symbol = S100G
| AltSymbols =; CABP1; CABP9K; CALB3; MGC138379
| OMIM = 302020
| ECnumber =
  | Homologene = 36150
| MGIid = 104528
| GeneAtlas_image1 = PBB_GE_S100G_207885_at_tn.png
  | Function = {{GNF_GO|id=GO:0005499 |text = vitamin D binding}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}}
| Component = {{GNF_GO|id=GO:0016323 |text = basolateral plasma membrane}} {{GNF_GO|id=GO:0016324 |text = apical plasma membrane}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 795
    | Hs_Ensembl = ENSG00000169906
    | Hs_RefseqProtein = NP_004048
    | Hs_RefseqmRNA = NM_004057
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 16578202
    | Hs_GenLoc_end = 16582714
    | Hs_Uniprot = P29377
    | Mm_EntrezGene = 12309
    | Mm_Ensembl = ENSMUSG00000040808
    | Mm_RefseqmRNA = NM_009789
    | Mm_RefseqProtein = NP_033919
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 158306097
    | Mm_GenLoc_end = 158308704
    | Mm_Uniprot = Q5VM59
  }}
}}
'''S100 calcium binding protein G''', also known as '''S100G''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: S100G S100 calcium binding protein G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=795| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.<ref name="entrez">{{cite web | title = Entrez Gene: S100G S100 calcium binding protein G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=795| accessdate = }}</ref>
| summary_text = This gene encodes [[calbindin]] D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca<sup>2+</sup> absorption by buffering Ca<sup>2+</sup> in the cytoplasm and increase ATP-dependent Ca<sup>2+</sup> transport in duodenal basolateral membrane vesicles.<ref name="entrez" />
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Balmain N |title=Calbindin-D9k. A vitamin-D-dependent, calcium-binding protein in mineralized tissues. |journal=Clin. Orthop. Relat. Res. |volume= |issue= 265 |pages= 265-76 |year= 1991 |pmid= 2009668 |doi=  }}
*{{cite journal  | author=Balmain N |title=Calbindin-D9k. A vitamin-D-dependent, calcium-binding protein in mineralized tissues |journal=Clin. Orthop. Relat. Res. |volume= |issue= 265 |pages= 265–76 |year= 1991 |pmid= 2009668 |doi=  }}
*{{cite journal  | author=Jeung EB, Krisinger J, Dann JL, Leung PC |title=Molecular cloning of the full-length cDNA encoding the human calbindin-D9k. |journal=FEBS Lett. |volume=307 |issue= 2 |pages= 224-8 |year= 1992 |pmid= 1379540 |doi=  }}
*{{cite journal  | vauthors=Fleet JC, Hock JM |title=Identification of osteocalcin mRNA in nonosteoid tissue of rats and humans by reverse transcription-polymerase chain reaction |journal=J. Bone Miner. Res. |volume=9 |issue= 10 |pages= 1565–73 |year= 1995 |pmid= 7817802 |doi=10.1002/jbmr.5650091009 }}
*{{cite journal  | author=Howard A, Legon S, Spurr NK, Walters JR |title=Molecular cloning and chromosomal assignment of human calbindin-D9k. |journal=Biochem. Biophys. Res. Commun. |volume=185 |issue= 2 |pages= 663-9 |year= 1992 |pmid= 1610358 |doi=  }}
*{{cite journal  | vauthors=Jeung EB, Leung PC, Krisinger J |title=The human calbindin-D9k gene. Complete structure and implications on steroid hormone regulation |journal=J. Mol. Biol. |volume=235 |issue= 4 |pages= 1231–8 |year= 1994 |pmid= 8308886 |doi= 10.1006/jmbi.1994.1076 }}
*{{cite journal  | author=Fleet JC, Hock JM |title=Identification of osteocalcin mRNA in nonosteoid tissue of rats and humans by reverse transcription-polymerase chain reaction. |journal=J. Bone Miner. Res. |volume=9 |issue= 10 |pages= 1565-73 |year= 1995 |pmid= 7817802 |doi= }}
*{{cite journal   |vauthors=Barley NF, Prathalingam SR, Zhi P, etal |title=Factors involved in the duodenal expression of the human calbindin-D9k gene |journal=Biochem. J. |volume=341 |issue=  3|pages= 491–500 |year= 1999 |pmid= 10417310 |doi=10.1042/0264-6021:3410491  | pmc=1220384 }}
*{{cite journal  | author=Miller EK, Word RA, Goodall CA, Iacopino AM |title=Calbindin-D9K gene expression in human myometrium during pregnancy and labor. |journal=J. Clin. Endocrinol. Metab. |volume=79 |issue= 2 |pages= 609-15 |year= 1994 |pmid= 8045984 |doi= }}
*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA Cloning Using In Vitro Site-Specific Recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948 }}
*{{cite journal  | author=Jeung EB, Leung PC, Krisinger J |title=The human calbindin-D9k gene. Complete structure and implications on steroid hormone regulation. |journal=J. Mol. Biol. |volume=235 |issue= 4 |pages= 1231-8 |year= 1994 |pmid= 8308886 |doi= 10.1006/jmbi.1994.1076 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Barley NF, Prathalingam SR, Zhi P, ''et al.'' |title=Factors involved in the duodenal expression of the human calbindin-D9k gene. |journal=Biochem. J. |volume=341 ( Pt 3) |issue=  |pages= 491-500 |year= 1999 |pmid= 10417310 |doi=  }}
*{{cite journal   |vauthors=Wang L, Klopot A, Freund JN, etal |title=Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1α |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=287 |issue= 5 |pages= G943–53 |year= 2004 |pmid= 15217781 |doi= 10.1152/ajpgi.00121.2004 | pmc=2701355 }}
*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ross MT, Grafham DV, Coffey AJ, etal |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 | pmc=2665286 }}
*{{cite journal | author=Wang L, Klopot A, Freund JN, ''et al.'' |title=Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1alpha. |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=287 |issue= 5 |pages= G943-53 |year= 2004 |pmid= 15217781 |doi= 10.1152/ajpgi.00121.2004 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Ross MT, Grafham DV, Coffey AJ, ''et al.'' |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{Calcium-binding proteins}}
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[[Category:S100 proteins]]

Latest revision as of 05:50, 11 September 2017

See also: Calbindin
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

S100 calcium-binding protein G (S100G) is a protein that in humans is encoded by the S100G gene.[1][2][3]

This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.[3]

References

  1. ↑ Howard A, Legon S, Spurr NK, Walters JR (1992). "Molecular cloning and chromosomal assignment of human calbindin-D9k". Biochem Biophys Res Commun. 185 (2): 663–9. doi:10.1016/0006-291X(92)91676-H. PMID 1610358.
  2. ↑ Jeung EB, Krisinger J, Dann JL, Leung PC (Sep 1992). "Molecular cloning of the full-length cDNA encoding the human calbindin-D9k". FEBS Lett. 307 (2): 224–8. doi:10.1016/0014-5793(92)80772-9. PMID 1379540.
  3. ↑ 3.0 3.1 "Entrez Gene: S100G S100 calcium binding protein G".

Further reading

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