Retinoblastoma CT: Difference between revisions

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{{Retinoblastoma}}
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==Overview==
==Overview==
Head and neck CT scan may be diagnostic of retinoblastoma. Findings on [[CT scan]] suggestive of retinoblastoma include retrolental mass that is usually calcified and a dense [[vitreous]] due to [[haemorrhage]].<ref name="radio">  Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10, 2015</ref> 
[[CT scan]] has been the standard [[Imaging studies|imaging study]] of [[retinoblastoma]]. [[Retinoblastoma]] usually appears as an intra-[[ocular]] [[mass]] with [[calcification]] (in 80% of the cases).
==CT scan==
==CT scan==
CT demonstrates a contrast-enhancing retrolental mass that is usually calcified. A dense [[vitreous]] due to [[haemorrhage]] is also common. Direct spread may occur into the orbit or occur along the [[optic nerve]] into the [[brain]]. Distant [[metastases]] are less common.<ref name="radio"> Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10 2015</ref>  
Retinoblastoma is [[Diagnose|diagnosed]] via indirect [[ophthalmoscopy]]. [[Imaging studies]] are usually done for these goals:<ref name="pmid22988349">{{cite journal |vauthors=Meel R, Radhakrishnan V, Bakhshi S |title=Current therapy and recent advances in the management of retinoblastoma |journal=Indian J Med Paediatr Oncol |volume=33 |issue=2 |pages=80–8 |date=April 2012 |pmid=22988349 |pmc=3439795 |doi=10.4103/0971-5851.99731 |url=}}</ref>
 
*To confirm the [[diagnosis]] in the difficult cases.
[[File:Coronal non contrast retinoblastoma.jpg|thumb|none|200px|Coronal non contrast CT scan showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Dalia Ibrahim. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-7]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
*To assess the involvement of extra-[[ocular]] extension or associated [[cerebral]] [[lesion]] in trilateral cases.
[[File:Axial non contrast retinoblastoma.jpg|thumb|none|200px|Axial non contrast CT scan showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Dalia Ibrahim. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-7]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
Findings on [[CT scan]] suggestive of/[[diagnostic]] of [[retinoblastoma]] include intra-[[ocular]] [[mass]] with [[calcification]].<br>
 
*[[CT scan]] has been the standard [[Imaging studies|imaging study]] in the evaluation of retinoblastoma due to its [[sensitivity]] in the detection of typical [[calcification]] of the [[tumor]] appearing in 80% of large [[tumors]].<br>
However, [[CT scan]] has less [[sensitivity]] compared to [[MRI]] in the [[diagnosis]] of [[tumor]] [[Infiltration (medical)|infiltration]] to the nearby structures.<ref name="pmid22988349">{{cite journal |vauthors=Meel R, Radhakrishnan V, Bakhshi S |title=Current therapy and recent advances in the management of retinoblastoma |journal=Indian J Med Paediatr Oncol |volume=33 |issue=2 |pages=80–8 |date=April 2012 |pmid=22988349 |pmc=3439795 |doi=10.4103/0971-5851.99731 |url=}}</ref><ref name="pmid12598449">{{cite journal |vauthors=Schueler AO, Hosten N, Bechrakis NE, Lemke AJ, Foerster P, Felix R, Foerster MH, Bornfeld N |title=High resolution magnetic resonance imaging of retinoblastoma |journal=Br J Ophthalmol |volume=87 |issue=3 |pages=330–5 |date=March 2003 |pmid=12598449 |pmc=1771559 |doi=10.1136/bjo.87.3.330 |url=}}</ref>
[[File:Coronal non contrast retinoblastoma.jpg|thumb|none|400px|Coronal non contrast CT scan showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Dalia Ibrahim. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-7]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
[[File:Axial non contrast retinoblastoma.jpg|thumb|none|400px|Axial non contrast CT scan showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Dalia Ibrahim. [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-7]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
==References==
==References==
{{reflist|2}}
{{reflist|2}}
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[[Category:Disease]]
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[3] Simrat Sarai, M.D. [4]

Overview

CT scan has been the standard imaging study of retinoblastoma. Retinoblastoma usually appears as an intra-ocular mass with calcification (in 80% of the cases).

CT scan

Retinoblastoma is diagnosed via indirect ophthalmoscopy. Imaging studies are usually done for these goals:[1]

  • To confirm the diagnosis in the difficult cases.
  • To assess the involvement of extra-ocular extension or associated cerebral lesion in trilateral cases.

Findings on CT scan suggestive of/diagnostic of retinoblastoma include intra-ocular mass with calcification.

However, CT scan has less sensitivity compared to MRI in the diagnosis of tumor infiltration to the nearby structures.[1][2]

Coronal non contrast CT scan showing retinoblastoma[3]
Axial non contrast CT scan showing retinoblastoma[3]

References

  1. 1.0 1.1 Meel R, Radhakrishnan V, Bakhshi S (April 2012). "Current therapy and recent advances in the management of retinoblastoma". Indian J Med Paediatr Oncol. 33 (2): 80–8. doi:10.4103/0971-5851.99731. PMC 3439795. PMID 22988349.
  2. Schueler AO, Hosten N, Bechrakis NE, Lemke AJ, Foerster P, Felix R, Foerster MH, Bornfeld N (March 2003). "High resolution magnetic resonance imaging of retinoblastoma". Br J Ophthalmol. 87 (3): 330–5. doi:10.1136/bjo.87.3.330. PMC 1771559. PMID 12598449.
  3. 3.0 3.1 Image courtesy of Dr. Dalia Ibrahim. Radiopaedia (original file [1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC