Retinoblastoma historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2] Simrat Sarai, M.D. [3]

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Overview

Retinoblastoma was first described in 1809 by Dr. James Wardrop. Then, Dr. Flexner, in 1891, was the first to discover the rosette structure within the tumor. In 1953, Dr. Kupfer was the first ophthalmologist who tried a combination of chemotherapy and radiotherapy for the treatment of the tumor.

Historical Perspective

Landmark Events in the Development of Treatment Strategies

References

  1. 1.0 1.1 1.2 Albert, Daniel M. (1987). "Historic Review of Retinoblastoma". Ophthalmology. 94 (6): 654–662. doi:10.1016/S0161-6420(87)33407-4. ISSN 0161-6420.
  2. Knudson AG (April 1971). "Mutation and cancer: statistical study of retinoblastoma". Proc. Natl. Acad. Sci. U.S.A. 68 (4): 820–3. PMC 389051. PMID 5279523.
  3. Dimaras H (March 2015). "Retinoblastoma genetics in India: From research to implementation". Indian J Ophthalmol. 63 (3): 219–26. doi:10.4103/0301-4738.156917. PMC 4448234. PMID 25971166.
  4. Jakobiec FA, Tso MO, Zimmerman LE, Danis P (May 1977). "Retinoblastoma and intracranial malignancy". Cancer. 39 (5): 2048–58. PMID 870165.


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