Portal vein thrombosis: Difference between revisions

	Portal vein thrombosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Portal vein thrombosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Portal vein thrombosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Portal vein thrombosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Portal vein thrombosis
CDC on Portal vein thrombosis
Portal vein thrombosis in the news
Blogs on Portal vein thrombosis
Directions to Hospitals Treating Portal vein thrombosis
Risk calculators and risk factors for Portal vein thrombosis

VisualWikitext

Latest revision as of 16:41, 28 December 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]

Synonyms and keywords:

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Portal vein thrombosis from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

Template:WH Template:WS

@@ Line 2: / Line 2: @@
 {{Portal vein thrombosis}}
-{{CMG}}; {{AE}}
+{{CMG}}; {{AE}} {{F.K}}
+{{SK}}
 ==[[Portal vein thrombosis overview|Overview]]==
@@ Line 11: / Line 13: @@
 ==[[Portal vein thrombosis pathophysiology|Pathophysiology]]==
-It is thought that [[vein thrombosis]] is caused by [[Virchow's triad]] which includes reduced portal blood flow, [[hypercoagulable state]], vascular endothelial injury. There are two mechanisms that contribute in loss of portal vein blood flow to liver, [[arterial]] rescue and venous rescue. It is a rapid process and takes a few days to start and 3-5 weeks to complete after portal vein obstruction. Collateral vessel joins to form [[cavernoma]] which connects the proximal and distal part of thrombosed portal vein. Finally, the portal vein becomes fibrosed, thin cord. All these events leads to low systemic vascular resistance and high cardiac output. These are the characterstic findings of hyperkinetic circulation.
 ==[[Portal vein thrombosis causes|Causes]]==
-Portal vein thrombosis may be caused by inherited prothrombotic disorders and acquired thrombophilic disorders. Less common causes of portal vein thrombosis include acquired conditions such as [[cirrhosis]] and[[hepatocellular carcinoma]] and procedures such as abdominal [[surgery]] or surgical injury of the portal vein axis and [[splenectomy]].
 ==[[Portal vein thrombosis differential diagnosis|Differentiating Portal vein thrombosis from Other Diseases]]==
-*Portal vein thrombosis must be differentiated from other diseases that cause abdominal pain, diarrhea, nausea and vomiting , such as [[Chronic pancreatitis|chronic pancreatitis,]] [[Pancreatic carcinoma]], [[Dumping syndrome]], [[Acute appendicitis]], [[Diverticulitis|acute diverticulitis]], [[Infective colitis]], [[Hepatitis|viral hepatitis]], [[Liver abscess]], [[Mesenteric ischemia]], [[Acute]] [[ischemic colitis]].
 ==[[Portal vein thrombosis epidemiology and demographics|Epidemiology and Demographics]]==
-The [[incidence]] of portal vein thrombosis in cirrhotic patients is unknown. The [[prevalence]] of portal vein thrombosis is approximately 5000-10,000 per 100,000 in overall cases of portal hypertension in developed counties and 40,000 per 100,000 in developing countries. The overall [[mortality rate]] of portal vein thrombosis is less than 10% except for patients with [[malignancy]] or [[cirrhosis]]. Patients of all age groups may develop portal vein thrombosis. There is no racial predilection to portal vein thrombosis. Portal vein thrombosis affects men and women equally.
 ==[[Portal vein thrombosis risk factors|Risk Factors]]==
-Common risk factors in the development of portal vein thrombosis include [[cirrhosis]], [[pancreatitis]], [[duodenal ulcer]], [[cholecystitis]], [[Crohn's disease|Crohn’s disease]], [[ulcerative colitis]] and [[cholecystectomy]], [[diverticulitis]] and [[appendicitis]] . Less common risk factors in the development of portal vein thrombosis include [[Oral contraceptive|oral contraceptives]], [[pregnancy]] or [[puerperium]], and [[hyperhomocysteinemia]].
 ==[[Portal vein thrombosis screening|Screening]]==
-There is insufficient evidence to recommend routine [[screening]] for portal vein thrombosis.
 ==[[Portal vein thrombosis natural history, complications and prognosis|Natural History, Complications, and Prognosis]]==
-If left untreated, patients with portal vein thrombosis may progress to develop portal cavernoma, gastric or [[esophageal varices]]/bleeding, [[hepatic encephalopathy]], [[splenomegaly]], portal biliopathy or cholangiopathy. Depending on the extent of the model for end-stage liver disease score at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as good.
 ==Diagnosis==

Portal vein thrombosis: Difference between revisions

Latest revision as of 16:41, 28 December 2017

Diagnosis

Treatment

Case Studies

Navigation menu