Portal vein thrombosis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Common risk factors in the development of portal vein thrombosis include cirrhosis, pancreatitis, duodenal ulcer, cholecystitis, Crohn’s disease, ulcerative colitis, cholecystectomy, diverticulitis, and appendicitis. Less common risk factors in the development of portal vein thrombosis include oral contraceptives, pregnancy or puerperium, and hyperhomocysteinemia.
Risk Factors
- Common risk factors in the development of portal vein thrombosis include: Hepatic cancer, cirrhosis, pancreatitis, duodenal ulcer, cholecystitis, Crohn’s disease, ulcerative colitis, and cholecystectomy.
Common Risk Factors
- Common risk factors in the development of portal vein thrombosis include:[1][2][3][4][5][6]
- Cirrhosis
- Focal inflammatory lesions
- Neonatal omphalitis, umbilical vein catheterization
- Diverticulitis
- Appendicitis
- Pancreatitis
- Duodenal ulcer
- Cholecystitis
- Tuberculous lymphadenitis
- Crohn’s disease, ulcerative colitis
- Cytomegalovirus hepatitis
- Injury to the portal venous system
- Splenectomy
- Colectomy and gastrectomy
- Cholecystectomy
- Liver transplantation
- Abdominal trauma
- Surgical portosystemic shunting
- Iatrogenic (fine needle aspiration of abdominal masses etc.)
- Preserved liver function with precipitating factors (splenectomy, surgical portosystemic shunting, TIPS dysfunction, thrombophilia)
- Advanced disease in the absence of obvious precipitating factors
Less common Risk Factors
References
- ↑ Webster GJ, Burroughs AK, Riordan SM (2005). "Review article: portal vein thrombosis -- new insights into aetiology and management". Aliment. Pharmacol. Ther. 21 (1): 1–9. doi:10.1111/j.1365-2036.2004.02301.x. PMID 15644039.
- ↑ Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). "Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment". World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
- ↑ Wang JT, Zhao HY, Liu YL (2005). "Portal vein thrombosis". HBPD INT. 4 (4): 515–8. PMID 16286254.
- ↑ Hoekstra J, Janssen HL (2009). "Vascular liver disorders (II): portal vein thrombosis". Neth J Med. 67 (2): 46–53. PMID 19299846.
- ↑ 5.0 5.1 Sobhonslidsuk A, Reddy KR (2002). "Portal vein thrombosis: a concise review". Am. J. Gastroenterol. 97 (3): 535–41. doi:10.1111/j.1572-0241.2002.05527.x. PMID 11922544.
- ↑ Webster GJ, Burroughs AK, Riordan SM (2005). "Review article: portal vein thrombosis -- new insights into aetiology and management". Aliment. Pharmacol. Ther. 21 (1): 1–9. doi:10.1111/j.1365-2036.2004.02301.x. PMID 15644039.
- ↑ Denninger MH, Chaït Y, Casadevall N, Hillaire S, Guillin MC, Bezeaud A, Erlinger S, Briere J, Valla D (2000). "Cause of portal or hepatic venous thrombosis in adults: the role of multiple concurrent factors". Hepatology. 31 (3): 587–91. doi:10.1002/hep.510310307. PMID 10706547.
- ↑ Chawla Y, Duseja A, Dhiman RK (2009). "Review article: the modern management of portal vein thrombosis". Aliment. Pharmacol. Ther. 30 (9): 881–94. doi:10.1111/j.1365-2036.2009.04116.x. PMID 19678814.