Portal vein thrombosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]

Overview

The incidence of portal vein thrombosis in cirrhosis patients is unknown. The prevalence of portal vein thrombosis is approximately 5000-10,000 per 100,000 in overall cases of portal hypertension in developed counties and 40,000 per 100,000 in developing countries. The overall mortality rate of portal vein thrombosis is less than 10% except for patients with malignancy or cirrhosis. Patients of all age groups may develop portal vein thrombosis. There is no racial predilection to portal vein thrombosis. Portal vein thrombosis affects men and women equally.

Epidemiology and Demographics

Incidence

Prevalence

Mortality rate

Age

  • Patients of all age groups may develop portal vein thrombosis.[1]
  • The incidence of portal vein thrombosis increases with age and it commonly affects individuals 66-70 years in men and 69-74 years in women.[2]

Race

  • There is no racial predilection to portal vein thrombosis.

Gender

  • Portal vein thrombosis affects men and women equally.[2]

References

  1. 1.0 1.1 1.2 1.3 Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). "Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment". World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
  2. 2.0 2.1 2.2 Ogren M, Bergqvist D, Björck M, Acosta S, Eriksson H, Sternby NH (2006). "Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies". World J. Gastroenterol. 12 (13): 2115–9. PMC 4087695. PMID 16610067.
  3. Okuda K, Ohnishi K, Kimura K, Matsutani S, Sumida M, Goto N, Musha H, Takashi M, Suzuki N, Shinagawa T (1985). "Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients". Gastroenterology. 89 (2): 279–86. PMID 4007419.
  4. Francoz C, Belghiti J, Vilgrain V, Sommacale D, Paradis V, Condat B, Denninger MH, Sauvanet A, Valla D, Durand F (2005). "Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation". Gut. 54 (5): 691–7. doi:10.1136/gut.2004.042796. PMC 1774501. PMID 15831918.
  5. Fimognari FL, Violi F (2008). "Portal vein thrombosis in liver cirrhosis". Intern Emerg Med. 3 (3): 213–8. doi:10.1007/s11739-008-0128-0. PMID 18274708.
  6. Chawla YK, Bodh V (2015). "Portal vein thrombosis". J Clin Exp Hepatol. 5 (1): 22–40. doi:10.1016/j.jceh.2014.12.008. PMC 4415192. PMID 25941431.
  7. Parikh, Sameer; Shah, Riddhi; Kapoor, Prashant (2010). "Portal Vein Thrombosis". The American Journal of Medicine. 123 (2): 111–119. doi:10.1016/j.amjmed.2009.05.023. ISSN 0002-9343.

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