Peutz-Jeghers syndrome physical examination: Difference between revisions
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===Extremities=== | ===Extremities=== | ||
*Patches of hyperpigmentation on the hands and feet | *Patches of hyperpigmentation on the hands and feet<ref name="pmid25460448">{{cite journal| author=Hofmann S, Barth TF, Kornmann M, Henne-Bruns D| title=Appendix carcinoid associated with the Peutz-Jeghers syndrome. | journal=Int J Surg Case Rep | year= 2014 | volume= 5 | issue= 12 | pages= 964-7 | pmid=25460448 | doi=10.1016/j.ijscr.2014.06.024 | pmc=PMC4276270 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25460448 }} </ref> | ||
*[[Clubbing]] may be present, if lung cancer develops | *[[Clubbing]] may be present, if lung cancer develops | ||
*[[Cyanosis]] may be present, if lung cancer develops | *[[Cyanosis]] may be present, if lung cancer develops | ||
Revision as of 16:04, 16 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Common physical examination findings of Peutz-Jeghers syndrome include mucocutaneous hyperpigmentation, abdominal tenderness due to intussusception, bowel obstruction, and pallor due to anemia.
Physical Examination
Appearance of the Patient
- If cancer develops, patient may appear cachectic
Vitals
Temperature
- Fever may be present, if cancer develops
Respiratory Rate
- Tachypnea may be present, if lung cancer develops
Skin
- Jaundice may be present, if pancreatic cancer develops
Eyes
- Icteric sclera may be present
Throat
- Oral mucosa
- Mucocutaneous pigmentation causing patches of hyperpigmentation in the oral mucosa (gingiva, hard palate, buccal mucosa, and labial mucosa)[1]
Neck
- Lymph nodes may be present, if cancer develops
Lungs
- If lung cancer develops, the patient may present with the following:
- Pulmonary edema and rales may be present
- Wheezing may be present
- Consolidation may be present with reduced breath sounds on auscultation
- Rales may be present
- Egophony may be present
- Chest movement may be asymmetric
Abdomen
- Abdominal distention may be present
- Abdominal tenderness may be present
- Rebound tenderness may be present
- An acute abdomen may be present, if intussusception develops
- An abdominal mass may be present, if hepatic or pancreatic cancers develop
- Guarding may be present
- Hepatomegaly may be present, if hepatic cancer develops
Extremities
- Patches of hyperpigmentation on the hands and feet[1]
- Clubbing may be present, if lung cancer develops
- Cyanosis may be present, if lung cancer develops
References
- ↑ 1.0 1.1 Hofmann S, Barth TF, Kornmann M, Henne-Bruns D (2014). "Appendix carcinoid associated with the Peutz-Jeghers syndrome". Int J Surg Case Rep. 5 (12): 964–7. doi:10.1016/j.ijscr.2014.06.024. PMC 4276270. PMID 25460448.