Paget's disease of the breast other diagnostic studies: Difference between revisions

Jump to navigation Jump to search
(Created page with "{{Paget's disease of the breast}} {{CMG}} ==Overview== ==References== {{Reflist|2}} {{WH}} {{WS}} Category:Disease Category:Dermatology Category:Breast [[Cat...")
 
No edit summary
 
(10 intermediate revisions by 6 users not shown)
Line 1: Line 1:
__NOTOC__
{{Paget's disease of the breast}}
{{Paget's disease of the breast}}
{{CMG}}
{{CMG}};{{AE}} {{Preeti}}
==Overview==
The use of touch/scrape smears for cytological diagnosis is recommended to prevent delay in [[diagnosis]]. Mainly in patients who are reluctant to undergo other [[diagnostic]] [[procedures]] such as wedge [[biopsy]], shave [[biopsy]], [[surgical excision]]. A negative result does not exclude the [[diagnosis]] of Paget's disease of the breast. [[In vivo]] reflectance confocal [[microscopy]] allows visualization of the upper layers of the [[skin]] at a [[cellular resolution]], may also assist in the early [[diagnosis]] of Paget's disease in reluctant patients.
==Other Diasgnostic Findings==


==Overview==
===Cytology===
*The use of touch/scrape smears for [[Cytology|cytological]] [[diagnosis]] is recommended to prevent delay in [[diagnosis]].
*Mainly in patients who are reluctant to undergo other [[diagnostic]] [[procedures]] such as wedge [[biopsy]], shave [[biopsy]], surgical excision.
*Due to the difficulty in differentiating Paget's disease from [[inflammatory]] [[skin]] conditions or [[Squamous cell carcinoma of the skin|squamous neoplasia]] on [[cytology]], a [[biopsy]] of the [[nipple]] and areola is generally preferred for definitive [[diagnosis]].
*[[Cytology]] of [[skin]] scrapings many time display the presence of:
:*Single [[malignant]] [[cells]] with [[Vacuole|vacuolated]] [[cytoplasm]] and [[eccentric]] [[nuclei]]
:*Three dimensional [[cell]] aggregates
:*[[Acinar]] groups consistent with [[glandular]] differentiation
*A negative result does not exclude the [[diagnosis]] of Paget's disease of the breast.<ref name="pmid7529588">{{cite journal |vauthors=Lucarotti ME, Dunn JM, Webb AJ |title=Scrape cytology in the diagnosis of Paget's disease of the breast |journal=Cytopathology |volume=5 |issue=5 |pages=301–5 |date=October 1994 |pmid=7529588 |doi= |url=}}</ref><ref name="pmid8390930">{{cite journal |vauthors=Samarasinghe D, Frost F, Sterrett G, Whitaker D, Ingram D, Sheiner H |title=Cytological diagnosis of Paget's disease of the nipple by scrape smears: a report of five cases |journal=Diagn. Cytopathol. |volume=9 |issue=3 |pages=291–5 |date=1993 |pmid=8390930 |doi= |url=}}</ref>
 
===In vivo reflectance confocal microscopy===
[[In vivo]] reflectance confocal [[microscopy]] allows visualization of the upper layers of the [[skin]] at a [[cellular resolution]], may also assist in the early [[diagnosis]] of Paget's disease in reluctant patients.




==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


Line 15: Line 30:
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Breast]]
[[Category:Breast]]
[[Category:Oncology]]
[[Category:Dermatology patient information]]
[[Category:Dermatology patient information]]
[[Category:Oncology patient information]]
[[Category:Oncology patient information]]
[[Category:Patient information]]
[[Category:Patient information]]
[[Category:Mature chapter]]
[[Category:Mature chapter]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Gynecology]]
[[Category:Surgery]]

Latest revision as of 18:18, 14 March 2019

Paget's disease of the breast Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paget's disease of the breast from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Biopsy

Ultrasonography

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Paget's disease of the breast other diagnostic studies On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Paget's disease of the breast other diagnostic studies

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Paget's disease of the breast other diagnostic studies

CDC on Paget's disease of the breast other diagnostic studies

Paget's disease of the breast other diagnostic studies in the news

Blogs on Paget's disease of the breast other diagnostic studies

Directions to Hospitals Treating Paget's disease of the breast

Risk calculators and risk factors for Paget's disease of the breast other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]

Overview

The use of touch/scrape smears for cytological diagnosis is recommended to prevent delay in diagnosis. Mainly in patients who are reluctant to undergo other diagnostic procedures such as wedge biopsy, shave biopsy, surgical excision. A negative result does not exclude the diagnosis of Paget's disease of the breast. In vivo reflectance confocal microscopy allows visualization of the upper layers of the skin at a cellular resolution, may also assist in the early diagnosis of Paget's disease in reluctant patients.

Other Diasgnostic Findings

Cytology

  • A negative result does not exclude the diagnosis of Paget's disease of the breast.[1][2]

In vivo reflectance confocal microscopy

In vivo reflectance confocal microscopy allows visualization of the upper layers of the skin at a cellular resolution, may also assist in the early diagnosis of Paget's disease in reluctant patients.


References

  1. Lucarotti ME, Dunn JM, Webb AJ (October 1994). "Scrape cytology in the diagnosis of Paget's disease of the breast". Cytopathology. 5 (5): 301–5. PMID 7529588.
  2. Samarasinghe D, Frost F, Sterrett G, Whitaker D, Ingram D, Sheiner H (1993). "Cytological diagnosis of Paget's disease of the nipple by scrape smears: a report of five cases". Diagn. Cytopathol. 9 (3): 291–5. PMID 8390930.

Template:WH Template:WS