Non small cell lung cancer medical therapy stage IV: Difference between revisions
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{{familytree | | | | | | | | | G01 | | G02 | | | G01=<div style="float: left; text-align: left;">If the [[lung]] disease is curable, administer local therapy for the [[adrenal]] lesion:<br> | {{familytree | | | | | | | | | G01 | | G02 | | | G01=<div style="float: left; text-align: left;">If the [[lung]] disease is curable, administer local therapy for the [[adrenal]] lesion:<br> | ||
* Surgical [[adrenal]] resection<br>OR<br> | * Surgical [[adrenal]] resection<br>OR<br> | ||
* Radiation therapy<br> | * [[Non small cell lung cancer radiation therapy|Radiation therapy]]<br> | ||
OR<br> | OR<br> | ||
Administer therapy for metastatic disease in case of not curable lung lesions (click here for the treatment of | Administer therapy for metastatic disease in case of not curable lung lesions ([[Non small cell lung cancer medical therapy metastatic disease|click here for the treatment of metastatic disease]]) | ||
</div>|G02=What is the TN stage of the lung [[tumor]]?}} | </div>|G02=What is the TN stage of the lung [[tumor]]?}} | ||
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{{familytree | | | | | | | | | | | I01 | | I02 | | | | I01=<div style="float: left; text-align: left;"> | {{familytree | | | | | | | | | | | I01 | | I02 | | | | I01=<div style="float: left; text-align: left;"> | ||
* Surgical resection of lung [[tumor]] + adjuvant chemotherapy<br>OR<br> | * Surgical resection of lung [[tumor]] + adjuvant [[Non small cell lung cancer chemotherapy|chemotherapy]]<br>OR<br> | ||
* Neoadjuvant chemotherapy + surgical resection or stereotactic ablative radiation therapy<br>OR<br> | * Neoadjuvant [[Non small cell lung cancer chemotherapy|chemotherapy]] + surgical resection or [[Non small cell lung cancer radiation therapy#Stereotactic ablative radiotherapy|stereotactic ablative radiation therapy]]<br>OR<br> | ||
* Stereotactic ablative radiation | * [[Non small cell lung cancer radiation therapy#Stereotactic ablative radiotherapy|stereotactic ablative radiation therapy]]</div> | ||
|I02=<div style="float: left; text-align: left;">Administer therapy for metastatic disease in case of not curable lung lesions (click here for the treatment of | |I02=<div style="float: left; text-align: left;">Administer therapy for metastatic disease in case of not curable lung lesions ([Non small cell lung cancer medical therapy metastatic disease|click here for the treatment of metastatic disease]])</div>}} | ||
{{familytree/end}} | {{familytree/end}} | ||
Revision as of 19:14, 24 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alonso Alvarado, M.D. [2]
Overview
Medical Therapy for Stage IV Non-Small Cell Lung Cancer
The algorithms for the treatment of stage IV non small cell carcinoma of the lung are based on the 2014 NCCN Non-Small Cell Lung Cancer guidelines.[1]
Is pleural or pericardial effusion present (suggestive of M1a) or are findings suggestive of systemic metastasis (M1b) present? | |||||||||||||||||||||||||||||||||||||||||||||
M1a | M1b: solitary site systemic metastasis | ||||||||||||||||||||||||||||||||||||||||||||
Perform the following tests:
| Perform the following tests:
| ||||||||||||||||||||||||||||||||||||||||||||
Is the liquid extracted positive for malignant cells? | Are findings suggestive of adrenal metastasis or brain metastasis? | ||||||||||||||||||||||||||||||||||||||||||||
Yes | No | Adrenal | Brain | ||||||||||||||||||||||||||||||||||||||||||
Local therapy
PLUS | Perform a needle aspiration biopsy for metastasis confirmation | Surgical resection + adjuvant radiation therapy Radiation therapy alone:
PLUS | |||||||||||||||||||||||||||||||||||||||||||
If the lung disease is curable, administer local therapy for the adrenal lesion:
OR | What is the TN stage of the lung tumor? | ||||||||||||||||||||||||||||||||||||||||||||
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| Administer therapy for metastatic disease in case of not curable lung lesions ([Non small cell lung cancer medical therapy metastatic disease | {{{click here for the treatment of metastatic disease]])}}} | |||||||||||||||||||||||||||||||||||||||||||