Neuroblastoma history and symptoms: Difference between revisions

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==History==
==History==
*When evaluating a patient for neuroblastoma, you should take a detailed history of the presenting symptom (duration, onset, progression), a thorough past medical history review, and a review of any other associated symptoms. When obtaining the history focus on a possible associated syndromes such as:<ref name="wiki"> Medulloblastoma. Wikipedia (2015) https://en.wikipedia.org/wiki/Medulloblastoma Accessed on September 2015</ref><ref name="radio">Dr Bruno Di Muzio and Dr Frank Gaillard et al. Medulloblastoma. Radiopaedia (2015) http://radiopaedia.org/articles/medulloblastoma Accessed on September, 28th 2015</ref>
:* [[Neurofibromatosis type 1]] ([[von Recklinghausen disease]])
:* [[Beckwith-Wiedemann syndrome]]
:* [[DiGeorge syndrome]]
:* [[Hirschsprung disease]]
:* Hutchinson syndrome
:* [[Pepper syndrome]]


==Symptoms==
==Symptoms==

Revision as of 18:05, 7 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

History

  • When evaluating a patient for neuroblastoma, you should take a detailed history of the presenting symptom (duration, onset, progression), a thorough past medical history review, and a review of any other associated symptoms. When obtaining the history focus on a possible associated syndromes such as:[1][2]

Symptoms

  • General symptoms of neuroblastoma include:
  • However, the specific clinical presentation of neuroblastoma is determined by the exact anatomical location of the tumor:[1][3]
  • Neuroblastomas located in the abdomen present may with:
  • Neurblasotmas located in the posterior mediastinum present may with:
  • Neurblasotmas located in the retroperitoneum may present with:
  • Metastatic neurblasotma lesions located in the bone marrow may present with:
  • Neurblasotmas located in the head and neck may present with:
  • Visual changes
  • Facial bruising
  • Facial swelling


References

  1. 1.0 1.1 Medulloblastoma. Wikipedia (2015) https://en.wikipedia.org/wiki/Medulloblastoma Accessed on September 2015
  2. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Medulloblastoma. Radiopaedia (2015) http://radiopaedia.org/articles/medulloblastoma Accessed on September, 28th 2015
  3. Neuroblastoma Childhood: Symptoms and Signs. Cancer.net http://www.cancer.net/cancer-types/neuroblastoma-childhood/symptoms-and-signs Accessed on October, 7 2015

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