Neuroblastoma classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]
Overview
International neuroblastoma pathology classification system is used for the classification of neuroblastic tumors. It is subdivided in 02 main categories based on the morphologic features of neuroblastic tumors into; schwannian stroma-poor and schwannian stroma-rich/dominant.
Classification
- International neuroblastoma pathology classification, a system based on the framework of Shimada classification with minor modifications is proposed for international use in classification of neuroblastic tumors. [1][2][3]
- It is a biologically relevant and pathologically significant classification system based on the morphologic features of neuroblastic tumors,i-e,neuroblastoma, ganglioneuroblastoma and ganglioneuroma.[4][5]
Neuroblastic tumors | |||||||||||||||||||||||||||||
| Schwannian stroma-poor group | Schwannian stroma-rich/dominant group | ||||||||||||||||||||||||||||
Undifferentiated neuroblastoma Poorly differentiated neuroblastoma Differentiating neuroblastoma |
Nodular ganglioneuroblastoma Intermixed ganglioneuroblastoma Maturing ganglioneuroma Mature ganglioneuroma | ||||||||||||||||||||||||||||
References
- ↑ Neuroblastoma, Ganglioneuroblastoma and Ganglioneuroma. Stanford Medicine Surgical Pathology Criteria(2015) http://surgpathcriteria.stanford.edu/srbc/neuroblastoma-ganglioneuroblastoma-ganglioneuroma/ Accessed on October, 5 2015
- ↑ Shimada H, Umehara S, Monobe Y, Hachitanda Y, Nakagawa A, Goto S; et al. (2001). "International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group". Cancer. 92 (9): 2451–61. PMID 11745303.
- ↑ Shimada, Hiroyuki; Ambros, Inge M.; Dehner, Louis P.; Hata, Jun-ichi; Joshi, Vijay V.; Roald, Borghild; Stram, Daniel O.; Gerbing, Robert B.; Lukens, John N.; Matthay, Katherine K.; Castleberry, Robert P. (1999). "The International Neuroblastoma Pathology Classification (the Shimada system)". Cancer. 86 (2): 364–372. doi:10.1002/(SICI)1097-0142(19990715)86:2<364::AID-CNCR21>3.0.CO;2-7. ISSN 0008-543X.
- ↑ H. Shimada, I. M. Ambros, L. P. Dehner, J. Hata, V. V. Joshi, B. Roald, D. O. Stram, R. B. Gerbing, J. N. Lukens, K. K. Matthay & R. P. Castleberry (1999). "The International Neuroblastoma Pathology Classification (the Shimada system)". Cancer. 86 (2): 364–372. PMID 10421273. Unknown parameter
|month=ignored (help) - ↑ H. Shimada, I. M. Ambros, L. P. Dehner, J. Hata, V. V. Joshi & B. Roald (1999). "Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee". Cancer. 86 (2): 349–363. PMID 10421272. Unknown parameter
|month=ignored (help)