Neuroblastoma surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]Haytham Allaham, M.D. [3]
Overview
Surgical intervention is curative as a single therapeutic modality for management of low risk neuroblastoma patients. In intermediate risk patients, surgical intervention must be followed by chemotherapy. However, the benefits of surgery to achieve complete tumor resection in high risk patients with metastatic disease is not clearly demonstrated.
Surgery
- Surgical intervention alone may be curative as a single therapeutic modality for the management of low risk neuroblastoma patients.[1]
- Surgical intervention must be followed by chemotherapy for the management of intermediate risk neuroblastoma patients.[2]
- The potential benefit of aggressive surgical approaches to achieve complete tumor resection in high-risk patients with metastatic disease has not been clearly demonstrated.[3][4][5][6][7]
- Surgical complications following neuroblastoma resection may include:[8]
- Intussusception
- Internal haemorrhage due to vessel injuries
- Nerve injuries
References
- ↑ Andrew M. Davidoff (2012). "Neuroblastoma". Seminars in pediatric surgery. 21 (1): 2–14. doi:10.1053/j.sempedsurg.2011.10.009. PMID 22248965. Unknown parameter
|month=ignored (help) - ↑ Suk-Bae Moon, Kwi-Won Park, Sung-Eun Jung & Woong-Jae Youn (2009). "Neuroblastoma: treatment outcome after incomplete resection of primary tumors". Pediatric surgery international. 25 (9): 789–793. doi:10.1007/s00383-009-2417-8. PMID 19629500. Unknown parameter
|month=ignored (help) - ↑ Neuroblastoma treatment–for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#section/_1 Accessed on October, 8 2015
- ↑ Valeria Smith & Jennifer Foster (2018). "High-Risk Neuroblastoma Treatment Review". Children (Basel, Switzerland). 5 (9). doi:10.3390/children5090114. PMID 30154341. Unknown parameter
|month=ignored (help) - ↑ E. Stanton Adkins, Robert Sawin, Robert B. Gerbing, Wendy B. London, Katherine K. Matthay & Gerald M. Haase (2004). "Efficacy of complete resection for high-risk neuroblastoma: a Children's Cancer Group study". Journal of pediatric surgery. 39 (6): 931–936. PMID 15185228. Unknown parameter
|month=ignored (help) - ↑ Thorsten Simon, Beate Haberle, Barbara Hero, Dietrich von Schweinitz & Frank Berthold (2013). "Role of surgery in the treatment of patients with stage 4 neuroblastoma age 18 months or older at diagnosis". Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 31 (6): 752–758. doi:10.1200/JCO.2012.45.9339. PMID 23284039. Unknown parameter
|month=ignored (help) - ↑ Victoria Castel, J. A. Tovar, E. Costa, J. Cuadros, A. Ruiz, V. Rollan, J. I. Ruiz-Jimenez, R. Perez-Hernandez & A. Canete (2002). "The role of surgery in stage IV neuroblastoma". Journal of pediatric surgery. 37 (11): 1574–1578. PMID 12407542. Unknown parameter
|month=ignored (help) - ↑ Neuroblastomas. Patient (2015) http://patient.info/doctor/neuroblastomas Accessed on October, 11 2015